Enhanced Pertussis Surveillance (EPS)
Enhanced Pertussis Surveillance is built upon the existing National Notifiable Diseases Surveillance System (NNDSS) for pertussis in six participating EIP states and is characterized by improved completeness and quality of data, augmented data collection and routine isolate collection. Following the identification of a pertussis case, a standardized case report form is completed using information collected during patient and physician interview. Isolates are collected, when available, and routinely shipped to CDC for further laboratory characterization. Because the number of pertussis isolates available for laboratory characterization has declined nationally, EPS sites have incorporated methods to increase isolate collection in their catchment areas, ranging from the establishment of sentinel clinics to promoting free, centralized testing at state public health laboratories.
While the primary objective of enhanced pertussis surveillance is to collect epidemiologic data and isolates from cases of B. pertussis, the EPS system is also capturing case data and isolates for other Bordetella species, including B. parapertussis, B. bronchiseptica, and B. holmesii. When available, epidemiologic information on these other Bordetella species will be incorporated into the enhanced pertussis surveillance dataset and isolates will be submitted to CDC.
Sites are encouraged to incorporate methods to increase the yield of identified pertussis cases in the catchment area. Methods for improving case ascertainment include encouraging providers to submit specimens directly to state public health laboratories for centralized testing as well as active education of providers and public health personnel within the catchment area about pertussis and the goals of EPS.
- Clinical Case Definition
- a cough illness lasting ≥2 weeks with at least one of the following: paroxysms of coughing, inspiratory "whoop," and/or posttussive vomiting, without other apparent cause (as reported by a health professional).
- Confirmed Case
- an acute cough illness of any duration, with isolation of B. pertussis from a clinical specimen, OR
- a case that meets the clinical case definition and is confirmed by polymerase chain reaction (PCR), OR
- a case that meets the clinical definition and is epidemiologically linked directly to a laboratory-confirmed case.
- Probable Case
- a case that meets the clinical case definition, is not laboratory-confirmed by culture or PCR, and is not epidemiologically linked directly to a laboratory-confirmed case.
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