Complications of SCD: Kidney Problems

At a glance

Sickle cell disease (SCD) is a group of inherited blood disorders associated with severe pain and complications that can affect the entire body. This page provides information on SCD and kidney problems.

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Sickled cells can cause reduced blood flow to the kidneys, leading to kidney damage and chronic kidney disease. The kidneys are an organ that filters waste from blood and produces urine. When the kidney does not get enough oxygen, kidney cells can die early, making it harder for the kidneys to function properly. This can affect the kidney's ability to filter out waste and can lead to excessive urination.

Signs and symptoms

Some signs and symptoms include:

  • Frequent urination
  • Nighttime bedwetting
  • High blood pressure
  • Bloody urine
  • Nausea and vomiting
  • Fatigue
  • Shortness of breath