Complications of SCD: Kidney Problems

For Everyone

At a glance

Sickle cell disease (SCD) is a group of inherited blood disorders associated with severe pain and complications that can affect the entire body. This page provides information on SCD and kidney problems.

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Overview

Sickled cells can cause reduced blood flow to the kidneys, leading to kidney damage and chronic kidney disease. The kidneys are an organ that filters waste from blood and produces urine. When the kidney does not get enough oxygen, kidney cells can die early, making it harder for the kidneys to function properly. This can affect the kidney's ability to filter out waste and can lead to excessive urination.

Signs and symptoms

Some signs and symptoms include:

  • Frequent urination
  • Nighttime bedwetting
  • High blood pressure
  • Bloody urine
  • Nausea and vomiting
  • Fatigue
  • Shortness of breath


Content Source
National Center on Birth Defects and Developmental Disabilities (NCBDDD)
About This Page
Published: May 15, 2024
Updated: May 15, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 7, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.