Vaccination

Two shingles vaccines are licensed and recommended in the United States. Zoster vaccine live (ZVL, Zostavax) has been used since 2006, and recombinant zoster vaccine (RZV, Shingrix), has been used since 2017, and is recommended as the preferred shingles vaccine.

Shingles is a painful rash that usually develops on one side of the body, often the face or torso. The rash consists of blisters that typically scab over in 7 to 10 days and clears up within 2 to 4 weeks. Some people describe the pain as an intense burning sensation. For some people, the pain can last for months or even years after the rash goes away. This long-lasting pain is called postherpetic neuralgia (PHN), and it is the most common complication of shingles. Your risk of getting shingles and PHN increases as you get older.

Two vaccines are licensed in the United States and recommended Advisory Committee on Immunization Practices (ACIP) to prevent shingles. Zoster vaccine live (ZVL, Zostavax) has been used since 2006. Recombinant zoster vaccine (RZV, Shingrix) has been used since 2017, and is recommended by ACIP as the preferred shingles vaccine. Zostavax may still be used to prevent shingles in healthy adults 60 years and older. For example, you could use Zostavax if a person is allergic to Shingrix, prefers Zostavax, or requests immediate vaccination and Shingrix is not available.

Shingrix Fact Sheets