Clinical Information
Each year, at least 1.7 million adults in America develop sepsis.
Nearly 270,000 Americans die as a result of sepsis.
1 in 3 patients who dies in a hospital has sepsis.
Surveillance and Epidemiology
Tools
- Hospital Toolkit for Adult Sepsis Surveillancepdf icon [PDF – 32 pages]
Centers for Disease Control and Prevention
August 2018
Presentations and Media Interviews
- A Matter of Life and Death: How States Are Tackling Sepsis as Public Policyexternal icon
Association of State and Territorial Health Officials Public Health Review podcast
November 25, 2019 - Hospital Toolkit for Adult Sepsis Surveillance Webinar
Society of Critical Care Medicine Critical Care Quality Summit
September 25, 2018
Publications
- Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shockexternal icon
JAMA Network Open
July 7, 2020 - Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012–2018*external icon
Critical Care Medicine
March 2020 - A National Approach to Pediatric Sepsis Surveillanceexternal icon
Pediatrics
December 2019 - Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Dataexternal icon
Critical Care Medicine
May 24, 2019 - Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisonsexternal icon
Critical Care Medicine
April 2019 - Using Objective Clinical Data to Track Progress on Preventing and Treating Sepsis — CDC’s New ‘Adult Sepsis Event’ Surveillance Strategy external icon
BMJ Quality & Safety
April 2019 - Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shockexternal icon
Critical Care Medicine
November 2018 - Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsisexternal icon
Critical Care Medicine
July 2018 - Variability in Determining Sepsis Time Zero and Bundle Compliance Rates for the Centers for Medicare and Medicaid Services SEP-1 Measureexternal icon
Infection Control & Hospital Epidemiology
June 22, 2018 - Risk of Subsequent Sepsis Within 90 Days After a Hospital Stay by Type of Antibiotic Exposure.external icon
Clinical Infectious Diseases
March 10, 2018 - Enhancing Recovery from Sepsis: A Reviewexternal icon
JAMA
January 2, 2018 - Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014 external icon
JAMA
October 3, 2017 - Varying Estimates of Sepsis Mortality Using Death Certificates and Administrative Codes — United States, 1999–2014external icon
Morbidity and Mortality Weekly Report
April 8, 2016
Prevention
Education
- The Sepsis Alliance Instituteexternal icon
Sepsis Alliance
2020 - Surviving Sepsis Campaignexternal icon
Society of Critical Care Medicine
2020 - Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [Video – 1:04]
Centers for Disease Control and Prevention
June 8, 2017 - Your Guide to Infection Control and Prevention: A Webinar Series: Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis pdf icon[PDF – 78 KB]
Centers for Disease Control and Prevention
May 17, 2017 - Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part Imedia iconexternal icon
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 2media iconexternal icon
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 3media iconexternal icon
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 4 media iconexternal icon
Quality Improvement Organizations
October 20, 2016–February 9, 2017
- Empowering Nurses for Early Sepsis Recognition [Video-1:01:40]
Centers for Disease Control and Prevention
October 25, 2016 - Advances in Sepsis: Protecting Patients Throughout the Lifespan [Video-58:47]
Centers for Disease Control and Prevention
October 25, 2016 - Think Sepsis and Act Fast [Video-4:17]external icon
Medscape CDC Expert Commentary
September 26, 2016 - Making Health Care Safer. Think Sepsis. Time Matters. pdf icon[PDF – 4 pages]
Centers for Disease Control and Prevention Vital Signs
August 2016
Presentations
- Government Funding for Sepsis Research [Video-2:01:54]
University of Illinois Interdisciplinary Sepsis & COVID-19 Symposium
September 28, 2020
Publications
- Combatting Sepsis: A Public Health Perspective external icon
Clinical Infectious Diseases
May 29, 2018 - Vital Signs: Epidemiology of Sepsis: Prevalence of Health Care Factors and Opportunities for Prevention
Morbidity and Mortality Weekly Report
August 26, 2016
Treatment
Tools
- Sepsis Early Recognition and Treatmentexternal icon
American College of Emergency Physicians
Publications
- Toward a More Nuanced Approach to the Early Administration of Intravenous Fluids in Patients With Sepsis.external icon
JAMA Network Open
December 7, 2018 - Current Sepsis Mandates Are Overly Prescriptive, and Some Aspects May Be Harmful.external icon
Critical Care Medicine
December 4, 2018
Clinical Guidelines
Children
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Childrenexternal icon
Pediatric Critical Care Medicine
February 2020 - Guidelines and Bundles for Pediatric Patientsexternal icon
Society of Critical Care Medicine
2020 - Sepsis Quality & Patient Safety Programexternal icon
Children’s Hospital Association
Adults
- Guidelines and Bundles for Adult Patientsexternal icon
Society of Critical Care Medicine
2016
Page last reviewed: December 7, 2020