Technical Resources & Guidelines
Surveillance and Epidemiology
Tools
- Hospital Toolkit for Adult Sepsis Surveillance [PDF – 32 pages]
Centers for Disease Control and Prevention
August 2018
Presentations and Media Interviews
- A Matter of Life and Death: How States Are Tackling Sepsis as Public Policy
Association of State and Territorial Health Officials Public Health Review podcast
November 25, 2019 - Hospital Toolkit for Adult Sepsis Surveillance Webinar
Society of Critical Care Medicine Critical Care Quality Summit
September 25, 2018
Publications
- Prevalence and Outcomes of Previously Healthy Adults Among Patients Hospitalized With Community-Onset Sepsis
Chest
July 2022 - Prevalence, Clinical Characteristics, and Outcomes of Sepsis Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Versus Other Pathogens in Hospitalized Patients With COVID-19
Critical Care Explorations
May 13, 2022 - Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals
JAMA Network Open
December 20, 2021 - SEP-1—Taking the Measure of a Measure
JAMA Network Open
December 20, 2021 - Epidemiology, Outcomes, and Trends of Patients With Sepsis and Opioid-Related Hospitalizations in U.S. Hospitals
Critical Care Medicine
December 1, 2021 - Characteristics and Outcomes of Clinic Visits Immediately Preceding Sepsis Hospitalization
American Journal of Critical Care
March 1, 2021 - Surveillance Strategies for Tracking Sepsis Incidence and Outcomes
The Journal of Infectious Diseases
July 21, 2020 - Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shock
JAMA Network Open
July 7, 2020 - Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012–2018*
Critical Care Medicine
March 2020 - A National Approach to Pediatric Sepsis Surveillance
Pediatrics
December 2019 - Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data
Critical Care Medicine
May 24, 2019 - Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons
Critical Care Medicine
April 2019 - Using Objective Clinical Data to Track Progress on Preventing and Treating Sepsis — CDC’s New ‘Adult Sepsis Event’ Surveillance Strategy
BMJ Quality & Safety
April 2019 - Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shock
Critical Care Medicine
November 2018 - Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsis
Critical Care Medicine
July 2018 - Variability in Determining Sepsis Time Zero and Bundle Compliance Rates for the Centers for Medicare and Medicaid Services SEP-1 Measure
Infection Control & Hospital Epidemiology
June 22, 2018 - Healthcare utilization and Infection in the week prior to sepsis hospitalization
Critical Care Medicine
April 2018 - Risk of Subsequent Sepsis Within 90 Days After a Hospital Stay by Type of Antibiotic Exposure.
Clinical Infectious Diseases
March 10, 2018 - Enhancing Recovery from Sepsis: A Review
JAMA
January 2, 2018 - Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014
JAMA
October 3, 2017 - Management of Sepsis and Septic Shock
JAMA
February 28, 2017 - Varying Estimates of Sepsis Mortality Using Death Certificates and Administrative Codes — United States, 1999–2014
Morbidity and Mortality Weekly Report
April 8, 2016
Prevention
Education
- The Sepsis Alliance Institute
Sepsis Alliance - Surviving Sepsis Campaign
Society of Critical Care Medicine - Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [Video – 1:04]
Centers for Disease Control and Prevention
June 8, 2017 - Your Guide to Infection Control and Prevention: A Webinar Series: Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [PDF – 78 KB]
Centers for Disease Control and Prevention
May 17, 2017 - Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part I
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 2
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 3
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 4
Quality Improvement Organizations
October 20, 2016–February 9, 2017
- Empowering Nurses for Early Sepsis Recognition [Video-1:01:40]
Centers for Disease Control and Prevention
October 25, 2016 - Advances in Sepsis: Protecting Patients Throughout the Lifespan [Video-58:47]
Centers for Disease Control and Prevention
October 25, 2016 - Think Sepsis and Act Fast [Video-4:17]
Medscape CDC Expert Commentary
September 26, 2016 - Making Health Care Safer. Think Sepsis. Time Matters. [PDF – 4 pages]
Centers for Disease Control and Prevention Vital Signs
August 2016
Presentations and Media Interviews
- EMS: The Link Between Disaster Medicine and Sepsis
Journal of Emergency Medical Services
December 9, 2021 - Government Funding for Sepsis Research [Video-2:01:54]
University of Illinois Interdisciplinary Sepsis & COVID-19 Symposium
September 28, 2020
Publications
- Combatting Sepsis: A Public Health Perspective
Clinical Infectious Diseases
May 29, 2018 - Vital Signs: Epidemiology of Sepsis: Prevalence of Health Care Factors and Opportunities for Prevention
Morbidity and Mortality Weekly Report
August 26, 2016
Treatment
Tools
- Sepsis Early Recognition and Treatment
American College of Emergency Physicians
Clinical Guidelines
Children
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children
Pediatric Critical Care Medicine
February 2020 - Guidelines and Bundles for Pediatric Patients
Society of Critical Care Medicine
2020 - Sepsis Quality & Patient Safety Program
Children’s Hospital Association
Adults
- International Guidelines for Management of Sepsis and Septic Shock 2021
Society of Critical Care Medicine
2021
Page last reviewed: August 9, 2022