Information For Clinicians
The first symptoms of monkeypox include fever, malaise, headache, and sometimes sore throat and cough. A distinguishing feature of monkeypox from smallpox is lymphadenopathy (swollen lymph nodes). This typically occurs with fever onset, 1 to 2 days before rash onset, or rarely with rash onset. Lymph nodes may swell in the neck (submandibular & cervical), armpits (axillary), or groin (inguinal) and occur on both sides of the body or just one.
You can recognize potential monkeypox infection based on the similarity of its clinical course to that of ordinary discrete smallpox.
- Page last reviewed: December 7, 2016
- Page last updated: May 11, 2015
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