Vaccines are the best way to help prevent pneumococcal disease; chemoprophylaxis is not recommended generally.
CDC recommends pneumococcal vaccination for
- All children younger than 5 years old
- People 5 through 64 years old who are at increased risk for pneumococcal disease
- Adults 65 years old or older
See Pneumococcal vaccination: Information for healthcare professionals for information on all pneumococcal vaccine recommendations by vaccine, age, and indication.
Understanding and implementing pneumococcal vaccination recommendations
- Examples: Complete pneumococcal vaccine schedules for adults
- Mobile app: PneumoRecs VaxAdvisor
In general, CDC does not recommend chemoprophylaxis for close contacts of patients with pneumococcal disease. Secondary cases of invasive pneumococcal infection are uncommon.
Chemoprophylaxis for children with asplenia
The American Academy of Pediatrics typically recommends daily antimicrobial prophylaxis with oral penicillin V for children with functional or anatomic asplenia, especially those with sickle cell disease. In general, clinicians should consider antimicrobial prophylaxis (in addition to vaccination) for all children with asplenia younger than 5 years of age and for at least 1 year after splenectomy.
- Adult immunization schedules
- Birth through 18 years and catch-up immunization schedules
- PneumoRecs VaxAdvisor mobile app
- Vaccine information statements
American Academy of Pediatrics. Antimicrobial prophylaxis. In: Kimberlin DW, Brady MT, Barnett ED, Lynfield R, Sawyer MH, eds. Red Book: 2021–2024 Report on Infectious Diseases, 32nd ed. Elk Grove Village, IL; 2021.