CDC recommends pneumococcal vaccination for all infants, young children, and older adults. CDC also recommends clinicians vaccinate older children and adults who are at increased risk for pneumococcal disease. See Pneumococcal Vaccination: Information for Healthcare Professionals for information on all pneumococcal vaccine recommendations by vaccine, age, and indication.
In general, CDC does not recommend chemoprophylaxis for close contacts of patients with pneumococcal disease. Secondary cases of invasive pneumococcal infection are uncommon.
The American Academy of Pediatrics typically recommends daily antimicrobial prophylaxis with oral penicillin V or G for children with functional or anatomic asplenia, especially those with sickle-cell disease. In general, clinicians should consider antimicrobial prophylaxis (in addition to immunization) for all children with asplenia younger than 5 years of age and for at least 1 year after splenectomy.
American Academy of Pediatrics. Antimicrobial therapy for treatment and prophylaxis. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, eds. Red Book: 2015 Report of the Committee on Infectious Diseases, 30th ed. Elk Grove Village, IL; 2015:72.
- Pink Book’s Chapter on Pneumococcal Disease
Epidemiology and Prevention of Vaccine-Preventable Diseases textbook
- Pneumococcal Disease Professional Practice Toolkitexternal icon
The National Foundation for Infectious Diseases offers ready-to-use resources to educate patients about pneumococcal disease