Iron, tris(dimethyldithiocarbamato)-
RTECS #
NO8750000
CAS #
Updated
June 2018
Molecular Weight
416.51
Molecular Formula
C9H18N3S6·Fe
Synonyms
Aafertis
Bercema fertam 50
Carbamic acid, dimethyldithio-, iron salt
Carbamodithioic acid, dimethyl-, iron complex
Dimethylcarbamodithioic acid, iron complex
Dimethylcarbamodithioic acid, iron(3+) salt
Dimethyldithiocarbamic acid, iron salt
Dimethyldithiocarbamic acid, iron(3+) salt
Eisen(III)-tris(N,N-dimethyldithiocarbamat) (German)
Eisendimethyldithiocarbamat (German)
ENT 14,689
Ferbam
Ferbam (ACGIH:OSHA)
Ferbam 50
Ferberk
Fermate
Ferradow
Ferric dimethyldithiocarbamate
Fuklasin Ultra
Fuklazin
Hexaferb
Iron dimethyldithiocarbamate
Iron, tris(dimethylcarbamodithioato-S,S')-, (OC-6-11)-
Karbam Black
Liromate
Stauffer ferbam
Trimanzone
Tris(dimethyldithiocarbamato)iron
Tris(N,N-dimethyldithiocarbamato) iron(111)
Vancide FE95
Bercema fertam 50
Carbamic acid, dimethyldithio-, iron salt
Carbamodithioic acid, dimethyl-, iron complex
Dimethylcarbamodithioic acid, iron complex
Dimethylcarbamodithioic acid, iron(3+) salt
Dimethyldithiocarbamic acid, iron salt
Dimethyldithiocarbamic acid, iron(3+) salt
Eisen(III)-tris(N,N-dimethyldithiocarbamat) (German)
Eisendimethyldithiocarbamat (German)
ENT 14,689
Ferbam
Ferbam (ACGIH:OSHA)
Ferbam 50
Ferberk
Fermate
Ferradow
Ferric dimethyldithiocarbamate
Fuklasin Ultra
Fuklazin
Hexaferb
Iron dimethyldithiocarbamate
Iron, tris(dimethylcarbamodithioato-S,S')-, (OC-6-11)-
Karbam Black
Liromate
Stauffer ferbam
Trimanzone
Tris(dimethyldithiocarbamato)iron
Tris(N,N-dimethyldithiocarbamato) iron(111)
Vancide FE95
Mutation Data and Reference
| System Test | Route/Organism/Tissue | Dose | Reference |
|---|---|---|---|
| Cytogenetic Analysis | oral/mouse | 30 mg/kg | TCMUD8 22,451,2002 |
| DNA repair | /Bacillus subtilis | 2 µg/disc | MUREAV 40,19,1976 |
| mutation in microorganisms | /Other microorganisms | 1000 ppm (-enzymatic activation step) | MMAPAP 50,233,1973 |
| mutation in microorganisms | /Salmonella typhimurium | 50 µg/plate (+enzymatic activation step) | CSHCAL 4,267,1977 |
| mutation in microorganisms | /Salmonella typhimurium | 200 µg/plate (-enzymatic activation step) | MBENDX 14,377,1986 |
| sperm morphology | oral/mouse | 5 gm/kg/5D-continuous | MUREAV 224,405,1989 |
Reproductive Effects Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/rat | 1140 mg/kg (6-15D pregnant) | Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) | TXAPA9 35,83,1976 |
| oral/rat | 536 mg/kg (16-22D preg/21D after birth) | Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) | TXAPA9 35,83,1976 |
| oral/rat | 3479 mg/kg (16-22D preg/21D after birth) | Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive) Reproductive: Effects on newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4) | TXAPA9 35,83,1976 |
| oral/mouse | 5 gm/kg (5D male) | Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) | MUREAV 224,405,1989 |
| subcutaneous/mouse | 41760 µg/kg (6-14D pregnant) | Reproductive: Effects on embryo or fetus: Extra embryonic structures (e.g., placenta, umbilical cord) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) Reproductive: Effects on embryo or fetus: Fetal death | NTIS** PB223-160 |
Tumorigenic Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/mouse | lowest published toxic dose: 3500 mg/kg/78W- intermittent | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Lung, Thorax, or Respiration: Tumors Liver: Tumors | NTIS** PB223-159 |
| subcutaneous/mouse | lowest published toxic dose: 100 mg/kg | Tumorigenic: Carcinogenic by RTECS criteria Blood: Tumors | NTIS** PB223-159 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| In Vitro/Human, kidney | Inhibitor Concentration (20 percent kill): 17.78 µmol/L/2H | In Vitro Toxicity Studies: Cell metabolic activity: Alamar Blue assay etc. | TIVIEQ 40,66,2017 |
| In Vitro/Human, kidney | Inhibitor Concentration (20 percent kill): 33.88 µmol/L/2H | Endocrine: Other changes | TIVIEQ 40,66,2017 |
| intraperitoneal/guinea pig | lowest published lethal dose: 2300 mg/kg | JAPMA8 41,662,1952 | |
| intraperitoneal/mouse | lethal dose (50 percent kill): 3 gm/kg | JAPMA8 41,662,1952 | |
| intraperitoneal/rabbit | lowest published lethal dose: 1500 mg/kg | JAPMA8 41,662,1952 | |
| intraperitoneal/rat | lethal dose (50 percent kill): 2700 mg/kg | JAPMA8 41,662,1952 | |
| oral/guinea pig | lowest published lethal dose: 2 gm/kg | JAPMA8 41,662,1952 | |
| oral/mouse | lethal dose (50 percent kill): 3400 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Excitement Behavioral: Ataxia | JTEHD6 4,93,1978 |
| oral/rabbit | lowest published lethal dose: 3 gm/kg | JAPMA8 41,662,1952 | |
| oral/rat | lethal dose (50 percent kill): 1130 mg/kg | FATOAO 32,356,1969 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/Dog | lowest published toxic dose: 9125 mg/kg/1Y- continuous | Behavioral: Convulsions or effect on seizure threshold Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | JPETAB 118,174,1956 |
| oral/rat | lowest published toxic dose: 45 gm/kg/30D- continuous | Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | JAPMA8 41,662,1952 |
| oral/rat | lowest published toxic dose: 91250 mg/kg/2Y- continuous | Brain and Coverings: Other degenerative changes Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | JPETAB 118,174,1956 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 5 mg/m3 | DTLVS* TLV/BEI,2013 |
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-Not classifiable as a human carcinogen | DTLVS* TLV/BEI,2013 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Animal Inadequate Evidence | IMEMDT 12,121,1976 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Human No Adequate Data | IMEMDT 12,121,1976 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Group 3 | IMSUDL 7,56,1987 |
| TOXICOLOGY REVIEW | FEREAC 72,32570,2007 | |
| TOXICOLOGY REVIEW | FEREAC 72,53449,2007 | |
| TOXICOLOGY REVIEW | HUTOX* -,561,1996 | |
| TOXICOLOGY REVIEW | HETOEA 26,321,2007 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 | |
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES | Supported | RBREV* -,173,1998 |
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 10 mg/m3 | DTLVS* 3,113,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 10 mg/m3, JUL2008 | |
| Occupational Exposure Limit-AUSTRIA | MAK-TMW 10 mg/m3, inhal, 2007 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 1 mg(Fe)/m3, MAR2002 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 10 mg/m3, MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 5 mg/m3, MAY2011 | |
| Occupational Exposure Limit-FRANCE | VME 10 mg/m3, FEB2006 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 5 mg/m3, NOV2011 | |
| Occupational Exposure Limit-KOREA | time-weighted average 10 mg/m3, 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 10 mg/m3, JAN2002 | |
| Occupational Exposure Limit-NORWAY | time-weighted average 1 mg(Fe)/m3, JAN1999 | |
| Occupational Exposure Limit-PERU | time-weighted average 10 mg/m3, JUL2005 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 10 mg/m3, inhal, JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 10 mg/m3, 2003 | |
| Occupational Exposure Limit-TURKEY | time-weighted average 15 mg/m3, JAN1993 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 15 mg/m3 | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO FERBAM-air | 10H time-weighted average 10 mg/m3 | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code M0362; Number of Industries 1; Total Number of Facilities 291; Number of Occupations 1; Total Number of Employees Exposed 3205 | |
| National Occupational Hazard Survey 1974 | Hazard Code M0362; Number of Industries 1; Total Number of Facilities 12; Number of Occupations 1; Total Number of Employees Exposed 72 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health