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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, pentyl ester

RTECS #

AJ1925000

CAS #

628-63-7

Updated

September 2013

Molecular Weight

130.21

Molecular Formula

C7H14O2

Synonyms

1-Pentanol acetate
1-Pentyl acetate
Acetate d'amyle (French)
Acetic acid, amyl ester
Amyl acetate
Amyl acetic ester
Amylazetat (German)
Amylester kyseliny octove (Czech)
Birnenoel
n-Amyl acetate (ACGIH:OSHA)
n-Pentyl acetate
Octan amylu (Polish)
Pent-acetate
Pent-acetate 28
Pentyl acetate
Primary amyl acetate

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /human 300 ppmJIHTAB 25,282,1943

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 5000 mg/m3/30MEye: Conjunctiva irritation

Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Other changes
AHYGAJ 78,260,1913
inhalation/rat Lethal concentration: >3000 ppm/6HNTIS** OTS0558878
intraperitoneal/guinea pig lowest published lethal dose: 1500 mg/kgBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferasesAIHAAP 35,21,1974
oral/rabbit lethal dose (50 percent kill): 7400 mg/kg85JCAE -,357,1986
oral/rat lethal dose (50 percent kill): >1600 mg/kgNTIS** OTS0556694

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 600 ppm/2W- intermittentBehavioral: Somnolence (general depressed activity)JJATDK 20,463,2000

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 50 ppm;short term exposure limit 100 ppmDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWAMIHAB 21,28,1960

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,292,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 100 ppm (525 mg/m3)DTLVS* 3,12,1971
Occupational Exposure Limit-AUSTRALIAtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm (541 mg/m3), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm(540 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 50 ppm (266 mg/m3), MAY2011
Occupational Exposure Limit-ECtime-weighted average 270 mg/m3 (50 ppm);short term exposure limit 540 mg/m3 (100 ppm), JUN2000
Occupational Exposure Limit-FRANCEVME 50 ppm (270 mg/m3), VLE 100 ppm (540), FEB2006
Occupational Exposure Limit-GERMANYMAK 50 ppm (270 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 270 mg/m3, short term exposure limit 540 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm (540 mg/m3), NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 50 ppm (266.3 mg/m3), ceiling concentration 100 ppm (532.5 mg/m3), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 100 ppm (530 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 100 ppm (530 mg/m3);short term exposure limit 150 ppm (800 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 100 ppm (532 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 50 ppm (260 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 50 ppm (266 mg/m3); short term exposure limit 100 ppm (532 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 250 mg/m3, MAC(short term exposure limit) 500 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 100 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 100 ppm (500 mg/m3);short term exposure limit 150 ppm (800 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 50 ppm (260 mg/m3), JAN2011
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 50 ppm (270 mg/m3);short term exposure limit 100 ppm (541 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO n-AMYL ACETATE-air10H time-weighted average 100 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M1226; Number of Industries 142; Total Number of Facilities 21065; Number of Occupations 108; Total Number of Employees Exposed 265437; Total Number of Female Employees Exposed 91128
National Occupational Hazard Survey 1974Hazard Code M1226; Number of Industries 48; Total Number of Facilities 4502; Number of Occupations 56; Total Number of Employees Exposed 37718

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Esters I, 1450
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
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