Toluenediamine

RTECS #

XS9445000

CAS #

25376-45-8; 26764-44-3; 30143-13-6
See: NMAM or OSHA Methods

Updated

July 2010

Molecular Weight

122.19

Molecular Formula

C₇H₁₀N₂

Synonyms

Benzenediamine, ar-methyl-
Diaminotoluene
Methylphenylenediamine
RCRA waste number U221
TDA 8020
Tolylenediamine

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
intraperitoneal/mouse	lethal dose (50 percent kill): 240 mg/kg		ZHYGAM 29,395,1983
intraperitoneal/rat	lethal dose (50 percent kill): 230 mg/kg		ZHYGAM 29,395,1983
intravenous/mouse	lethal dose (50 percent kill): 90 mg/kg		ZHYGAM 29,395,1983
intravenous/rat	lethal dose (50 percent kill): 350 mg/kg		ZHYGAM 29,395,1983
oral/mouse	lethal dose (50 percent kill): 350 mg/kg		ZHYGAM 29,395,1983
oral/rat	lethal dose (50 percent kill): 270 mg/kg		ZHYGAM 29,395,1983
skin/rat	lethal dose (50 percent kill): 463 mg/kg	Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change Lung, Thorax, or Respiration: Cyanosis Kidney, Ureter, and Bladder: Other changes in urine composition	NTIS** OTS0544321

Organization	Standard	Reference
TOXICOLOGY REVIEW		REPTED 29,10,2010

Organization	Standard	Reference
Occupational Exposure Limit-RUSSIA	short term exposure limit 2 mg/m³, Skin, JUN2003

Organization	Standard	Reference
National Occupational Exposure Survey 1983	Hazard Code M2689; Number of Industries 1; Total Number of Facilities 4; Number of Occupations 3; Total Number of Employees Exposed 413
National Occupational Hazard Survey 1974	Hazard Code M2689; Number of Industries 1; Total Number of Facilities 15; Number of Occupations 1; Total Number of Employees Exposed 29

Organization	Reference
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, PROPOSED RULE	FEREAC 47,27009,82
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

Page last reviewed: November 16, 2018