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Registry of Toxic Effects of Chemical Substances (RTECS)

Talc (powder), containing no asbestos fibers

RTECS #

WW2710000

CAS #

14807-96-6; 11119-41-8; 12420-12-1; 37232-12-5; 99638-63-8; 110540-41-5

Updated

March 2016

Molecular Weight

96.33

Molecular Formula

H203Si·3/4Mg

Synonyms

Agalite
Asbestine
B 13
B 13 (mineral)
B 13(mineral)
B 9
B 9 (talc)
Beaver White 200
Beaver White 325
Cimflex 606
Circron MP
CP 10-40
CP 38-33
Crown Talc W 83
Crown Talc Z
Crystalite CRS 6002
CT 8 (mineral)
Cubic Master
Desertalc 57
Emtal 500
Emtal 549
Emtal 596
Emtal 599
EX-IT
Fibrene C 400
Finntalc C10
Finntalc M05
Finntalc M15
Finntalc P40
Finntalc PF
FW-XO
IT Extra
LMR 100
Micro Ace K1
Micro Ace L1
Micron White 5000A
Micron White 5000P
Micron White 5000S
Microtalco IT Extra
Mistron 139
Mistron 2SC
Mistron frost P
Mistron RCS
Mistron Star
Mistron super frost
Mistron vapor
MP 12-50
MP 25-38
MP 40-27
MP 45-26
MST
Mussolinite
Nytal 200
Nytal 400
P 3
P 3 (Mineral)
PK-C
PK-N
Polytal 4641
Polytal 4725
Silicate: talc, containing no asbestos (OSHA)
Steawhite
Supreme
Supreme dense
Talc
Talc (ACGIH)
Talc, containing no asbestos fibers
Talcan PK-P
Talcron CP 44-31
Talcum
TY 80

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /human 300 µg/3D- intermittent mild85DKA8 -,127,1977

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 18 mg/m3/6H/2Y- intermittentTumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Bronchogenic carcinoma

Endocrine: Tumors
NTPTR* NTP-TR-421,1993
inhalation/rat toxic concentration: 11 mg/m3/1Y- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors
43GRAK -,389,1979

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 20400 µg/m3/6H/26D- intermittentLung, Thorax, or Respiration: Other changesENVRAL 49,233,1989
inhalation/rat lowest published toxic concentration: 17 mg/m3/6H/26D- intermittentLung, Thorax, or Respiration: Other changesENVRAL 49,233,1989

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2 mg/m3 (resp particulate)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited Evidence (perinIMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 42,185,1987
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 42,185,1987
International Agency for Research on Cancer (IARC)Cancer Review:Human Limited Evidence (perineIMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate Evidence (inhIMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMSUDL 7,349,1987
International Agency for Research on Cancer (IARC)Cancer Review:Group 3 (inhaled)IMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)Cancer Review:Group 2B (perineal use)IMEMDT 93,412,2010
TOXICOLOGY REVIEWEMMUEG 39,69,2002
TOXICOLOGY REVIEWDIMON* 40,258,1994
TOXICOLOGY REVIEWENTOX* -,131,2005

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2.5 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 2 mg/m3, resp, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 2 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.3 f/cc, carc, MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg/m3, NOV2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.3 f/cc, NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.5 mg/m3 (resp. dust), 2 mg/m3 (total dust), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 2 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2 mg/m3 (respirable), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 mg/m3 (respirable dust), JAN2002
Occupational Exposure Limit-PERUtime-weighted average 2 mg/m3, JUL2005
Occupational Exposure Limit-SWEDENtime-weighted average 2 mg/cm3 (total dust);time-weighted average 1 mg/cm3 (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 2 mg/m3, resp, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1 mg/m3 (resp. dust), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 20 mppcf, respirable dustCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 20 mppcf, respirable dustCFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 20 mppcf, respirable dustCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 20 mppcfCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TALC (containing no asbestos)-air10H 2 mg/m3NIOSH* PHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code X9093; Number of Industries 2; Total Number of Facilities 273; Number of Occupations 2; Total Number of Employees Exposed 4245; Total Number of Female Employees Exposed 590
National Occupational Exposure Survey 1983Hazard Code 71055; Number of Industries 313; Total Number of Facilities 82650; Number of Occupations 192; Total Number of Employees Exposed 1367384; Total Number of Female Employees Exposed 348973
National Occupational Hazard Survey 1974Hazard Code 71055; Number of Industries 243; Total Number of Facilities 38349; Number of Occupations 149; Total Number of Employees Exposed 527353

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NCI Carcinogenesis Studies (inhal);clear evidence:rat
NCI Carcinogenesis Studies (inhal);no evidence:mouse
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