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Registry of Toxic Effects of Chemical Substances (RTECS)

Molybdenum

RTECS #

QA4680000

CAS #

7439-98-7

Updated

October 2017

Molecular Weight

95.94

Molecular Formula

Mo

Synonyms

Molybdate

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisinhalation/rat19500 µg/m3GTPZAB 24(9),33,1980

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 6050 µg/kg (35W prior to copulation)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
GISAAA 42(8),30,1977
oral/rat 5800 µg/kg (30W prior to copulation/1-20D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemFATOAO 41,620,1978
oral/mouse 448 mg/kg (multigenerations)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Effects on embryo or fetus: Fetal death
AEHLAU 23,102,1971

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intratracheal/rabbit lowest published lethal dose: 70 mg/kgLung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)NTIS** PB249-458

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rabbit lowest published toxic dose: 66.5 mg/kg/19W- intermittentLiver: Other changes

Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN5* -,317,1989
oral/rat lowest published toxic dose: 7 mg/kg/2W- intermittentLiver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
VCVN5* -,317,1989

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 3 mg/m3 (resp);time-weighted average 10 mg/m3 (inhal)DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWJAVMA4 164,277,1974
TOXICOLOGY REVIEWFOREAE 7,313,1942
TOXICOLOGY REVIEWKOTTAM 11,1300,1975
TOXICOLOGY REVIEWENTOX* -,145,2005
TOXICOLOGY REVIEWHBTME* ,731,2007
TOXICOLOGY REVIEWHTOPA* 1,595,2002
TOXICOLOGY REVIEWMUREAV 674,31,2009
TOXICOLOGY REVIEWMUREAV 770,140,I2

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-AUSTRALIAtime-weighted average 10 mg(Mo)/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 10 mg/m3;KZW 20 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 10 mg/m3, MAR2002
Occupational Exposure Limit-KOREAtime-weighted average 10 mg/m3, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 5 mg/m3, JAN2002
Occupational Exposure Limit-RUSSIAtime-weighted average 0.5 mg/m3, short term exposure limit 3 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 10 mg/m3 (total dust); time-weighted average 5 mg/m3 (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 10 mg/m3, inhal, JAN2011

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X5919; Number of Industries 2; Total Number of Facilities 29; Number of Occupations 6; Total Number of Employees Exposed 2426; Total Number of Female Employees Exposed 1114
National Occupational Exposure Survey 1983Hazard Code X5984; Number of Industries 5; Total Number of Facilities 187; Number of Occupations 11; Total Number of Employees Exposed 4474; Total Number of Female Employees Exposed 2432
National Occupational Exposure Survey 1983Hazard Code 48625; Number of Industries 173; Total Number of Facilities 15780; Number of Occupations 88; Total Number of Employees Exposed 238124; Total Number of Female Employees Exposed 4166
National Occupational Hazard Survey 1974Hazard Code 48625; Number of Industries 17; Total Number of Facilities 935; Number of Occupations 29; Total Number of Employees Exposed 6097

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements by ICP, 7300
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
NIOSH Analytical Method, 1994: Metals in urine, 8310
On EPA IRIS database
OSHA ANALYTICAL METHOD #ID121
OSHA ANALYTICAL METHOD #ID125G
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