Ethylenimine

RTECS #

KX5075000

CAS #

151-56-4
See: NMAM or OSHA Methods

Updated

December 2018

Molecular Weight

43.08

Molecular Formula

C₂H₅N

Synonyms

1H-Azirine, dihydro-
Aethylenimin (German)
Azacyclopropane
Aziran
Aziridin (German)
Aziridine
Dihydro-1H-azirine
Dihydroazirene
Dimethyleneimine
EI
ENT-50324
Ethyleenimine (Dutch)
Ethylene imine
Ethyleneimine
Ethyleneimine (ACGIH:OSHA)
Etilenimina (Italian)
RCRA waste number P054
TL 337

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /mouse	2 ppm/1M		JIHTAB 30,7,1948
eye /rabbit	2 mg	severe	AJOPAA 29,1363,1946
skin /rabbit	10 mg/24H open irritation test		JIHTAB 30,63,1948

Mutation Data and Reference

System Test	Route/Organism/Tissue	Dose	Reference
Cytogenetic Analysis	parenteral/Drosophila melanogaster	10 mmol/L	MUREAV 6,129,1968
Cytogenetic Analysis	lymphocyte/human	1 µmol/L/1H	ARTODN 46,61,1980
Cytogenetic Analysis	leukocyte/human	10 µmol/L/1H	22XWAN -,367,1970
Cytogenetic Analysis	lung/human	10 µmol/L	MUREAV 4,83,1967
Cytogenetic Analysis	intraperitoneal/rat	5 mg/kg	BJPCAL 6,357,1951
Cytogenetic Analysis	inhalation/rat	8 µg/L/17W	TPKVAL 13,51,1973
Cytogenetic Analysis	fibroblast/chicken	770 µmol/L	MUREAV 81,123,1981
Cytogenetic Analysis	intraperitoneal/mammal (species unspecified)	5 mg/kg	TPKVAL 11,111,1969
Cytogenetic Analysis	inhalation/rat	0.01 mg/L/45D- intermittent	TPKVAL 11,111,1969
Cytogenetic Analysis	inhalation/rat	0.6 mg/L/8D- intermittent	TPKVAL 11,111,1969
DNA Damage	inhalation/other insects	100 ppm	MUREAV 476,149,2001
DNA inhibition	intravaginal/mouse	1 pph	JIDEAE 62,378,1974
DNA inhibition	intraperitoneal/mouse	1 mg/kg	MUREAV 46,305,1977
DNA inhibition	HeLa cell/human	500 µmol/L	CNREA8 38,4445,1978
DNA repair	/Escherichia coli	1 pph	AGACBH 4,286,1974
DNA repair	/Salmonella typhimurium	1 pph	AGACBH 4,286,1974
DNA repair	/Bacillus subtilis	800 mg/L	EVSRBT 24,19,1981
Dominant Lethal Test	intraperitoneal/mouse	5 mg/kg	EVSRBT 24,943,1981
Dominant Lethal Test	parenteral/other insects	20 mmol/L	MUREAV 15,67,1972
Dominant Lethal Test	inhalation/Drosophila melanogaster	1250 ppm	SOGEBZ 11,883,1975
gene conversion and mitotic recombination	/Saccharomyes cerevisiae	1 pph	AGACBH 4,286,1974
gene conversion and mitotic recombination	inhalation/Drosophila melanogaster	2700 ppm	SOGEBZ 11,1073,1975
heritable translocation test	parenteral/Drosophila melanogaster	6500 µmol/L	IDZAAW 39,155,1964
micronucleus test	multiple/non-mammalian species	500 ppb/8D-continuous	MUREAV 125,275,1984
mutation in mammalian somatic cells	ovary/hamster	2 mg/L	MUREAV 94,449,1982
mutation in microorganisms	/Aspergillus nidulans	10 mmol/L (-enzymatic activation step)	SOGEBZ 6,220,1970
mutation in microorganisms	/Neurospora crassa	20 µg/plate (-enzymatic activation step)	MUREAV 53,297,1978
mutation in microorganisms	/Saccharomyes cerevisiae	1 pph (-enzymatic activation step)	AGACBH 4,286,1974
mutation in microorganisms	/Bacillus subtilis	19300 nmol/L (-enzymatic activation step)	JACBBD 25,73,1975
mutation in microorganisms	/Other microorganisms	600 ppm/2H-continuous (-enzymatic activation step)	DBANAD 31,1477,1978
mutation in microorganisms	/Other microorganisms	500 mg/L (-enzymatic activation step)	AMBBBR 6,15,1974
mutation in microorganisms	/Other microorganisms	2000 ppm (-enzymatic activation step)	SOGEBZ 7,948,1971
mutation in microorganisms	/Other microorganisms	100 mmol/plate (-enzymatic activation step)	PCJOAU 15,482,1981
mutation in microorganisms	/Other microorganisms	1 pph (-enzymatic activation step)	ANTBAL 27,738,1982
mutation in microorganisms	/Escherichia coli	100 mmol/plate (-enzymatic activation step)	PCJOAU 22,292,1988
mutation in microorganisms	/Other microorganisms	100 mmol/plate (-enzymatic activation step)	PCJOAU 22,292,1988
mutation in microorganisms	/Salmonella typhimurium	1 pph (+enzymatic activation step)	AGACBH 4,286,1974
mutation in microorganisms	/Salmonella typhimurium	10 µg/plate (-enzymatic activation step)	PNASA6 72,5135,1975
sex chromosome loss and nondisjunction	multiple/Drosophila melanogaster	1 pph/8H-continuous	GNKAA5 21,958,1985
sex chromosome loss and nondisjunction	oral/Drosophila melanogaster	2 ppm	NTIS** PB81-160848
sex chromosome loss and nondisjunction	parenteral/Drosophila melanogaster	10 mmol/L	GENTAE 56,273,1967
sex chromosome loss and nondisjunction	intraperitoneal/Drosophila melanogaster	10 mmol/L	PNASA6 53,282,1965
specific locus test	parenteral/silkworm	2 mmol/L	MUREAV 7,425,1969
Unscheduled DNA Synthesis	parenteral/mouse	5 mg/kg	EVSRBT 24,943,1981

Reproductive Effects Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	800 µg/m³/24H (1D male)	Reproductive: Paternal effects: Testes, epididymis, sperm duct	TPKVAL 14,16,1975
inhalation/rat	19 mg/m³ (6W male)	Reproductive: Paternal effects: Testes, epididymis, sperm duct Reproductive: Maternal effects: Ovaries, fallopian tubes Reproductive: Effects on embryo or fetus: Fetal death	TPKVAL 9,59,1967
inhalation/rat	19 mg/m³ (6W male)	Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth) Reproductive: Effects on newborn: Behavioral	TPKVAL 9,59,1967
inhalation/rat	700 µg/m³ (17W male)	Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) Reproductive: Effects on newborn: Delayed effects	TPKVAL 9,59,1967
inhalation/rat	0.0007 gm/m³ (1-20D pregnant)	Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive: Effects on embryo or fetus: Fetal death	TPKVAL 13,70,1973
inhalation/rat	0.0002 gm/m³ (1-4D pregnant)	Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)	TPKVAL 13,70,1973
inhalation/rat	0.01 gm/m³ (51D male)	Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)	TPKVAL 8,41,1966
inhalation/rat	19 mg/m³ (45D male)	Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea) Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)	TPKVAL 9,59,1967
inhalation/rat	19 mg/m³ (45D male)	Reproductive: Effects on newborn: Behavioral Reproductive: Effects on newborn: Other postnatal measures or effects Reproductive: Effects on newborn: Delayed effects	TPKVAL 9,59,1967
inhalation/rat	0.7 mg/m³ (122D male)	Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) Reproductive: Effects on newborn: Other postnatal measures or effects Reproductive: Effects on newborn: Delayed effects	TPKVAL 9,59,1967
subcutaneous/mouse	41760 µg/kg (6-14D pregnant)	Reproductive: Specific developmental abnormalities: Central nervous system Reproductive: Specific developmental abnormalities: Eye, ear Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)	NTIS** PB223-160
subcutaneous/mouse	41760 µg/kg (6-14D pregnant)	Reproductive: Effects on embryo or fetus: Extra embryonic structures (e.g., placenta, umbilical cord) Reproductive: Effects on embryo or fetus: Fetal death	NTIS** PB223-160

Tumorigenic Data and References

Route/Organism	Dose	Effect	Reference
oral/mouse	lowest published toxic dose: 6500 µg/kg/5D- intermittent	Tumorigenic: Carcinogenic by RTECS criteria Liver: Tumors	VOONAW 27(5),88,1981
oral/mouse	lowest published toxic dose: 235 mg/kg/76W- continuous	Tumorigenic: Carcinogenic by RTECS criteria Lung, Thorax, or Respiration: Tumors Liver: Tumors	JNCIAM 42,1101,1969
subcutaneous/rat	toxic dose: 10 mg/kg/8W- intermittent	Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Tumorigenic: Tumors at site of application	BJPCAL 9,306,1954
subcutaneous/rat	lowest published toxic dose: 20 mg/kg/67D- intermittent	Tumorigenic: Neoplastic by RTECS criteria Tumorigenic: Tumors at site of application	BJPCAL 9,306,1954

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/guinea pig	Lowest published lethal concentration: 25 ppm/8H	Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion Lung, Thorax, or Respiration: Dyspnea Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)	JIHTAB 30,2,1948
inhalation/guinea pig	lethal concentration (50 percent kill): 170 ppm/1H		ENTOX* -,293,2005
inhalation/mouse	lethal concentration (50 percent kill): 150 ppm/1H		ENTOX* -,293,2005
inhalation/mouse	lowest published toxic concentration: 0.1 gm/m³/2H	Lung, Thorax, or Respiration: Other changes	TPKVAL 10,25,1968
inhalation/mouse	lethal concentration (50 percent kill): 400 mg/m³/2H	Behavioral: Muscle weakness Lung, Thorax, or Respiration: Other changes Nutritional and Gross Metabolic: Body temperature decrease	TPKVAL 8,41,1966
inhalation/mouse	lethal concentration (50 percent kill): 0.4 gm/m³		TPKVAL 9,3,1967
inhalation/mouse	Lowest published lethal concentration: 0.64 gm/m³/2H	Lung, Thorax, or Respiration: Changes in pulmonary vascular resistance Liver: Other changes Kidney, Ureter, and Bladder: Changes in blood vessels or in circulation of kidney	TPKVAL 8,41,1966
inhalation/mouse	Lowest published lethal concentration: 0.24 gm/m³/2H	Kidney, Ureter, and Bladder: Changes in both tubules and glomeruli Blood: Changes in bone marrow not included in above Blood: Changes in spleen	TPKVAL 8,41,1966
inhalation/rabbit	Lowest published lethal concentration: 100 mg/m³/2H	Brain and Coverings: Other degenerative changes Lung, Thorax, or Respiration: Other changes Blood: Other changes	TPKVAL 8,41,1966
inhalation/rat	lowest published toxic concentration: 0.8 mg/m³	Peripheral Nerve and Sensation: Recording from peripheral motor nerve Lung, Thorax, or Respiration: Other changes	TPKVAL 14,16,1975
inhalation/rat	lowest published toxic concentration: 0.008 gm/m³/4H		TPKVAL 9,86,1967
inhalation/rat	lethal concentration (50 percent kill): 0.1 gm/m³/2H	Peripheral Nerve and Sensation: Recording from afferent nerve Lung, Thorax, or Respiration: Changes in pulmonary vascular resistance Kidney, Ureter, and Bladder: Changes in blood vessels or in circulation of kidney	TPKVAL 8,41,1966
inhalation/rat	lowest published toxic concentration: 0.01 gm/m³/4H	Eye: Lacrimation Behavioral: Irritability Lung, Thorax, or Respiration: Dyspnea	TPKVAL 8,41,1966
inhalation/rat	Lowest published lethal concentration: 15 ppm/8H		TOXID9 78,149,2004
inhalation/rat	lethal concentration (50 percent kill): 185 ppm/1H		ENTOX* -,293,2005
inhalation/rat	lethal concentration (50 percent kill): 100 mg/m³/2H		85GMAT -,67,1982
intraperitoneal/mouse	lethal dose (50 percent kill): 4 mg/kg	Kidney, Ureter, and Bladder: Urine volume increased	BJPCAL 25,223,1965
intraperitoneal/rat	lethal dose (50 percent kill): 3500 µg/kg	Kidney, Ureter, and Bladder: Urine volume increased	BJPCAL 21,581,1963
oral/mouse	lethal dose (50 percent kill): 15 mg/kg		ENTOX* -,293,2005
oral/rat	lethal dose (50 percent kill): 15 mg/kg	Behavioral: General anesthetic Gastrointestinal: Other changes Kidney, Ureter, and Bladder: Other changes	JIHTAB 23,259,1941
oral/rat	lethal dose (50 percent kill): 15 mg/kg		ENTOX* -,293,2005
skin/guinea pig	lethal dose (50 percent kill): 14 mg/kg		JIHTAB 30,63,1948
skin/guinea pig	lowest published toxic dose: 0.6 mg/kg	Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Respiratory depression Skin: After topical application: Corrosive	TPKVAL 8,41,1966
skin/rabbit	lowest published lethal dose: 50 mg/kg/1H	Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Respiratory depression Skin: After topical application: Corrosive	TPKVAL 8,41,1966
skin/rabbit	lowest published toxic dose: 10 mg/kg/3H	Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Respiratory depression Skin: After topical application: Corrosive	TPKVAL 8,41,1966
unreported route/mouse	lethal dose (50 percent kill): 15 mg/kg		BJCAAI 6,160,1952
unreported route/rat	lethal dose (50 percent kill): 0.015 mg/kg		TPKVAL 9,3,1967

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Peripheral Nerve and Sensation: Recording from peripheral motor nerve Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi Liver: Other changes	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Kidney, Ureter, and Bladder: Other changes Blood: Changes in spleen Blood: Changes in other cell count (unspecified)	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/30D- intermittent	Peripheral Nerve and Sensation: Recording from peripheral motor nerve Blood: Changes in other cell count (unspecified)	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Liver: Liver function tests impaired Kidney, Ureter, and Bladder: Changes primarily in glomeruli Kidney, Ureter, and Bladder: Proteinuria	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Blood: Luekopenia Blood: Angranulocytosis Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Immunological Including Allergic: Decrease in cellular immune response	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 0.4 mg/m³/122D- intermittent	Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) Reproductive: Paternal effects: Testes, epididymis, sperm duct	TOVEFN 9,50,1967
inhalation/rat	lowest published toxic concentration: 19 mg/m³/45D- intermittent	Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) Reproductive: Paternal effects: Testes, epididymis, sperm duct Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females)	TOVEFN 9,59,1967
inhalation/rat	lowest published toxic concentration: 19 mg/m³/45D- intermittent	Related to Chronic Data: Changes in testicular weight	TOVEFN 9,59,1967
inhalation/rat	lowest published toxic concentration: 700 µg/m³/4H/17W- intermittent	Kidney, Ureter, and Bladder: Proteinuria Blood: Changes in other cell count (unspecified) Immunological Including Allergic: Decrease in cellular immune response	TPKVAL 9,50,1967
inhalation/rat	lowest published toxic concentration: 10 mg/m³/4H/6W- intermittent	Behavioral: Muscle weakness Nutritional and Gross Metabolic: Weight loss or decreased weight gain	TPKVAL 8,41,1966
inhalation/rat	lowest published toxic concentration: 10 mg/m³/30D- intermittent	Reproductive: Paternal effects: Testes, epididymis, sperm duct Biochemical: Metabolism (intermediary): Effect on mitochondrial function	TPKVAL 14,16,1975
inhalation/rat	lowest published toxic concentration: 0.01 gm/m³/20D- intermittent	Nutritional and Gross Metabolic: Weight loss or decreased weight gain	TPKVAL 13,70,1973
inhalation/rat	lowest published toxic concentration: 0.01 gm/m³/51D- intermittent	Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females) Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Changes in testicular weight	TPKVAL 8,41,1966

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.5 ppm (skin)	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-Confirmed animal carcinogen	DTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)	Cancer Review:Animal Limited Evidence	IMEMDT 9,37,1975
International Agency for Research on Cancer (IARC)	Cancer Review:Animal Limited Evidence	IMEMDT 71,337,1999
International Agency for Research on Cancer (IARC)	Cancer Review:Human No Adequate Data	IMEMDT 9,37,1975
International Agency for Research on Cancer (IARC)	Cancer Review:Human No Adequate Data	IMEMDT 71,337,1999
International Agency for Research on Cancer (IARC)	Cancer Review:Group 2B	IMEMDT 71,337,1999
TOXICOLOGY REVIEW		ENTOX* -,293,2005
TOXICOLOGY REVIEW		MUREAV 584,1,2005
TOXICOLOGY REVIEW		RTOPDW 54,247,2009

Standards and Regulations

Organization	Standard	Reference
Mine Safety and Health Administration (MSHA) STANDARD-air	time-weighted average 0.5 ppm (1 mg/m³) (skin)	DTLVS* 3,111,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 0.5 ppm (0.88 mg/m³), Carcinogen, JUL2008
Occupational Exposure Limit-AUSTRIA	TRK-TMW 0.5 ppm (0.9 mg/m³);KZW 2 ppm (3.6 mg/m³), skin, 2007
Occupational Exposure Limit-BELGIUM	time-weighted average 0.5 ppm (0.89 mg/m³), Skin, Carcinogen, MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.5 ppm (1 mg/m³), skin, carc, MAY2011
Occupational Exposure Limit-FINLAND	short term exposure limit 0.5 ppm (0.89 mg/m³), skin, NOV2011
Occupational Exposure Limit-HUNGARY	ceiling concentration 0.9 mg/m³, Carcinogen, SEP2000
Occupational Exposure Limit-ICELAND	time-weighted average 0.5 ppm (1 mg/m³), carc, skin, NOV2011
Occupational Exposure Limit-JAPAN	Occupational Exposure Limit 0.5 ppm (0.88 mg/m³), skin, 2B carc, MAY2012
Occupational Exposure Limit-KOREA	time-weighted average 0.5 ppm (1 mg/m³), skin, 2006
Occupational Exposure Limit-MEXICO	time-weighted average 0.5 ppm (1 mg/m³) (skin), 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 0.5 ppm (0.88 mg/m³), skin, JAN2002
Occupational Exposure Limit-NORWAY	time-weighted average 0.5 ppm (1 mg/m³), JAN1999
Occupational Exposure Limit-PERU	time-weighted average 0.5 ppm (0.9 mg/m³), JUL2005
Occupational Exposure Limit-RUSSIA	short term exposure limit 0.02 mg/m³, Skin, JUN2003
Occupational Exposure Limit-SWEDEN	Group B Carcinogen, JUN2005
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.5 ppm (0.9 mg/m³), carc 2, skin, JAN2011
Occupational Exposure Limit-TURKEY	time-weighted average 0.5 ppm (1 mg/m³), Skin, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	see Code of Federal Regulations (CFR) 29,1926.1112	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 0.5 ppm (1 mg/m³) (skin)	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA)-cancer suspect agent		CFRGBR 29,1910.1012,1987

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHYLENEIMINE-air	Carcinogen use 29 Code of Federal Regulations (CFR) 1910.1012	NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983	Hazard Code M0492; Number of Industries 1; Total Number of Facilities 4; Number of Occupations 13; Total Number of Employees Exposed 1093
National Occupational Hazard Survey 1974	Hazard Code M0492; Number of Industries 2; Total Number of Facilities 19; Number of Occupations 17; Total Number of Employees Exposed 1712

Status in Federal Agencies

Organization	Reference
EPA GENETOX PROGRAM 1988, Positive/limited: Carcinogenicity-mouse/rat
EPA GENETOX PROGRAM 1988, Positive: Aspergillus-reversion; In vitro cytogenetics-human
EPA GENETOX PROGRAM 1988, Positive: CHO gene mutation
EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal; UDS in mouse germ cells
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-reciprocal translocation
EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
EPA GENETOX PROGRAM 1988, Positive: In vitro cytogenetics-human lymphocyte
EPA GENETOX PROGRAM 1988, Positive: N crassa-forward mutation; N crassa-reversion
EPA GENETOX PROGRAM 1988, Positive: S cerevisiae gene conversion
EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-forward mutation; S cerevisiae-homozygosis
EPA GENETOX PROGRAM 1988, Positive: S pombe-forward mutation
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Ethylenimine, 3514
On EPA IRIS database

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health