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Registry of Toxic Effects of Chemical Substances (RTECS)

Cyclohexanol, methyl-

RTECS #

GW0175000

CAS #

25639-42-3

Updated

September 2013

Molecular Weight

114.21

Molecular Formula

C7H14O

Synonyms

Hexahydrocresol
Hexahydromethylphenol
Methylcyclohexanol
Methylcyclohexanol (ACGIH:OSHA)
Methylhexalin
Metylocykloheksanol (Polish)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 500 ppmBehavioral: Antipsychotic

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
TGNCDL 2,55,1961
oral/rabbit lowest published lethal dose: 1750 mg/kgHBTXAC 1,194,1955
oral/rat lethal dose (50 percent kill): 1660 mg/kgJIHTAB 25,415,1943
skin/rabbit lowest published lethal dose: 6800 mg/kgHBTXAC 1,194,1955
subcutaneous/rat lethal dose (50 percent kill): 2900 mg/kgJIHTAB 25,415,1943

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 50 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 50 ppm (235 mg/m3)DTLWS* 3,23,1973
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 50 ppm (234 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 50 ppm (235 mg/m3);KZW 200 ppm (940 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 50 ppm (237 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 50 ppm (235 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 50 ppm (240 mg/m3), short term exposure limit 75 ppm (360 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 50 ppm (235 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 50 ppm (235 mg/m3), NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 50 ppm (230 mg/m3), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 50 ppm (235 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 50 ppm (235 mg/m3);short term exposure limit 75 ppm (350 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 50 ppm (234 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 25 ppm (115 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 50 ppm (234 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 50 mg/m3, MAC(short term exposure limit) 350 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 50 ppm, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 50 ppm (235 mg/m3), KZG-week 100 ppm (470 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 50 mg/m3, Skin, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 100 ppm (470 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 100 ppm (470 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 50 ppm (237 mg/m3);short term exposure limit 75 ppm (356 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 100 ppm (470 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 100 ppm (470 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 100 ppm (470 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 100 ppm (470 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO METHYLCYCLOHEXANOL-air10H time-weighted average 50 ppmNIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
NIOSH Analytical Method, 1994: Methylcyclohexanol, 1404
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