Cyanamide, calcium salt (1:1)

RTECS #

GS6000000

CAS #

156-62-7
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

80.11

Molecular Formula

CN₂·Ca

Synonyms

Alzodef
Calcium carbimide
Calcium cyanamid
Calcium cyanamide
Calcium cyanamide (ACGIH)
CCC
Cyanamid granular
Cyanamide calcique (French)
CY-L 500
Dormex
Lime-nitrogen
NCI-C02937
Nitrogen lime
Nitrolim
Nitrolime
USAF CY-2

Mutation Data and Reference

System Test	Route/Organism/Tissue	Dose	Reference
mutation in microorganisms	/Salmonella typhimurium	1 mg/plate (+enzymatic activation step)	ENMUDM 5(Suppl 1),3,1983

Tumorigenic Data and References

Route/Organism	Dose	Effect	Reference
oral/mouse	lowest published toxic dose: 170 gm/kg/2Y- continuous	Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Vascular: Tumors	NCITR* NCI-TR-163,1979

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lethal concentration (50 percent kill): >150 mg/m³/4H		85JFAN A053,1984
inhalation/rat	lowest published toxic concentration: 3000 mg/m³/20M	Behavioral: Somnolence (general depressed activity)	VCVN1* -,346,1988
intraperitoneal/mouse	lethal dose (50 percent kill): 100 mg/kg		NTIS** AD277-689
intravenous/mouse	lethal dose (50 percent kill): 282 mg/kg		NIIRDN 6,304,1982
intravenous/rat	lethal dose (50 percent kill): 125 mg/kg		NIIRDN 6,304,1982
oral/guinea pig	lethal dose (50 percent kill): 220 mg/kg	Behavioral: Irritability Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea	VCVN1* -,346,1988
oral/human	lowest published lethal dose: 571 mg/kg		34ZIAG -,149,1969
oral/mouse	lethal dose (50 percent kill): 334 mg/kg	Behavioral: Irritability Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea	VCVN1* -,346,1988
oral/mouse	lethal dose (50 percent kill): 334 mg/kg		NIIRDN 6,304,1982
oral/rabbit	lethal dose (50 percent kill): 350 mg/kg	Behavioral: Irritability Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea	VCVN1* -,346,1988
oral/rabbit	lethal dose (50 percent kill): 1400 mg/kg		PCOC** -,174,1966
oral/rat	lethal dose (50 percent kill): 158 mg/kg		NIIRDN 6,304,1982
oral/rat	lethal dose (50 percent kill): 250 mg/kg	Behavioral: Irritability Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea	VCVN1* -,346,1988
skin/rabbit	lethal dose (50 percent kill): 590 mg/kg		37ASAA 7,291,1979
unreported route/human	lowest published lethal dose: 571.4 mg/kg		VCVN1* -,346,1988
unreported route/rat	lethal dose (50 percent kill): 1 gm/kg		GUCHAZ 6,73,1973

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
oral/rat	lowest published toxic dose: 250 mg/kg/10D- intermittent	Behavioral: Tremor Lung, Thorax, or Respiration: Dyspnea Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)	VCVN1* -,347,1988

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.5 mg/m³	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-Not classifiable as a human carcinogen	DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEW		MUREAV 584,1,2005

Standards and Regulations

Organization	Standard	Reference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION		FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES	Cancelled	RBREV* -,299,1998
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 0.5 mg/m³, JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 0.5 mg/m³;KZW 5 mg/m³, inhal, skin, 2007
Occupational Exposure Limit-BELGIUM	time-weighted average 0.5 mg/m³, MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.5 mg/m³, MAY2011
Occupational Exposure Limit-FINLAND	time-weighted average 0.5 mg/m³, short term exposure limit 1.5 mg/m³, NOV2011
Occupational Exposure Limit-FRANCE	VME 0.5 mg/m³, FEB2006
Occupational Exposure Limit-GERMANY	MAK 1 mg/m³, inhal, skin, 2011
Occupational Exposure Limit-HUNGARY	time-weighted average 1 mg/m³, short term exposure limit 4 mg/m³, Skin, SEP2000
Occupational Exposure Limit-ICELAND	time-weighted average 0.5 mg/m³, NOV2011
Occupational Exposure Limit-KOREA	time-weighted average 0.5 mg/m³, 2006
Occupational Exposure Limit-MEXICO	time-weighted average 0.5 mg/m³;short term exposure limit 1 mg/m³, 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 0.5 mg/m³, JAN2002
Occupational Exposure Limit-NORWAY	time-weighted average 0.5 mg/m³, JAN1999
Occupational Exposure Limit-PERU	time-weighted average 0.5 mg/m³, JUL2005
Occupational Exposure Limit-RUSSIA	short term exposure limit 1 mg/m³, JUN2003
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.5 mg/m³, KZG-week 1.0 mg/m³, resp, skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 0.5 mg/m³, 2003
Occupational Exposure Limit-UNITED KINGDOM	time-weighted average 0.5 mg/m³;short term exposure limit 1 mg/m³, OCT2007

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CALCIUM CYANAMIDE-air	10H time-weighted average 0.5 mg/m³	NIOSH* DHHS #95-121,1995
National Occupational Exposure Survey 1983	Hazard Code 15730; Number of Industries 2; Total Number of Facilities 249; Number of Occupations 3; Total Number of Employees Exposed 4390
National Occupational Hazard Survey 1974	Hazard Code 15730; Number of Industries 2; Total Number of Facilities 287; Number of Occupations 2; Total Number of Employees Exposed 12607

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat	NCITR* NCI-TR-163,1979

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health