Cotton dust
RTECS #
GN2275000
CAS #
Updated
September 2013
Molecular Weight
N/R
Molecular Formula
N/R
Synonyms
Cotton dust (ACGIH)
Cotton dust, raw
Cotton dust, raw (OSHA)
Cotton dust, raw
Cotton dust, raw (OSHA)
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/guinea pig | lowest published toxic concentration: 2 mg/m3/6H | Lung, Thorax, or Respiration: Respiratory depression | VCVPS* -,212,1998 |
| inhalation/human | lowest published toxic concentration: 1.02 mg/m3/6H | VCVPS* -,212,1998 | |
| inhalation/human | lowest published toxic concentration: 1.02 mg/m3/6H | Lung, Thorax, or Respiration: Respiratory depression | VCVPS* -,212,1998 |
| inhalation/human | lowest published toxic concentration: 10000 mg/m3/10Y | Lung, Thorax, or Respiration: Cough Lung, Thorax, or Respiration: Dyspnea Lung, Thorax, or Respiration: Other changes | BJIMAG 17,1,1960 |
| inhalation/mammal (species unspecified) | Lethal concentration: >16250 mg/m3 | GTPZAB 35(4),38,1991 | |
| intraperitoneal/guinea pig | lethal dose (50 percent kill): 4 gm/kg | JDGRAX 5(1),93,1973 | |
| intraperitoneal/rat | lethal dose (50 percent kill): 2 gm/kg | JDGRAX 5(1),93,1973 | |
| oral/mouse | Lethal dose: >15 gm/kg | GTPZAB 35(4),38,1991 | |
| oral/rat | Lethal dose: >15 gm/kg | GTPZAB 35(4),38,1991 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/guinea pig | lowest published toxic concentration: 21 mg/m3/6H/1Y- intermittent | Lung, Thorax, or Respiration: Other changes Lung, Thorax, or Respiration: Changes in lung weight | TXAPA9 88,354,1987 |
| inhalation/guinea pig | lowest published toxic concentration: 580 µg/m3/6H/24W- intermittent | Lung, Thorax, or Respiration: Changes in lung weight Blood: Changes in leukocyte (WBC) count Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases | JEGPAY 54,171,1979 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.1 mg/m3 (thorac) | DTLVS* TLV/BEI,2013 |
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-Not classifiable as a human carcinogen | DTLVS* TLV/BEI,2013 |
| TOXICOLOGY REVIEW | JJOMDZ 14,199,1972 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 1 mg/m3 (dust) | DTLVS* 3,60,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.2 mg/m3, JUL2008 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 0.2 mg/m3, MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 0.5 mg/m3, MAY2011 | |
| Occupational Exposure Limit-FRANCE | VME 0.2 mg/m3, fiber, FEB2006 | |
| Occupational Exposure Limit-GERMANY | MAK 1.5 mg/m3, inhal, 2011 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 0.5 mg/m3, NOV2011 | |
| Occupational Exposure Limit-INDIA | time-weighted average 0.2 mg/m3, JAN1993 | |
| Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 1 mg/m3 (resp. dust), 4 mg/m3 (total dust), MAY2012 | |
| Occupational Exposure Limit-KOREA | time-weighted average 0.2 mg/m3, 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 0.2 mg/m3;short term exposure limit 0.6 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.2 mg/m3, JAN2002 | |
| Occupational Exposure Limit-SWEDEN | time-weighted average 0.5 mg/m3, JUN2005 | |
| Occupational Exposure Limit-SWITZERLAND | ceiling concentration 1.5 mg/m3, inhal, JAN2011 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 0.2 mg/m3, inhal, JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 0.2 mg/m3, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 1 mg/m3, JAN1993 | |
| Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 2.5 mg/m3 (inhal. dust), OCT2007 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 1 mg/m3, raw dust | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 1 ppm, raw dust | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | see 1910.1043 | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 1 mg/m3, raw dust | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COTTON DUST-air | lowest feasible concentration | NIOSH* DHHS #92-100,1992 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health