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Registry of Toxic Effects of Chemical Substances (RTECS)

Cotton dust

RTECS #

GN2275000

CAS #

Updated

September 2013

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Cotton dust (ACGIH)
Cotton dust, raw
Cotton dust, raw (OSHA)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/guinea pig lowest published toxic concentration: 2 mg/m3/6HLung, Thorax, or Respiration: Respiratory depressionVCVPS* -,212,1998
inhalation/human lowest published toxic concentration: 1.02 mg/m3/6HVCVPS* -,212,1998
inhalation/human lowest published toxic concentration: 1.02 mg/m3/6HLung, Thorax, or Respiration: Respiratory depressionVCVPS* -,212,1998
inhalation/human lowest published toxic concentration: 10000 mg/m3/10YLung, Thorax, or Respiration: Cough

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Other changes
BJIMAG 17,1,1960
inhalation/mammal (species unspecified) Lethal concentration: >16250 mg/m3GTPZAB 35(4),38,1991
intraperitoneal/guinea pig lethal dose (50 percent kill): 4 gm/kgJDGRAX 5(1),93,1973
intraperitoneal/rat lethal dose (50 percent kill): 2 gm/kgJDGRAX 5(1),93,1973
oral/mouse Lethal dose: >15 gm/kgGTPZAB 35(4),38,1991
oral/rat Lethal dose: >15 gm/kgGTPZAB 35(4),38,1991

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/guinea pig lowest published toxic concentration: 21 mg/m3/6H/1Y- intermittentLung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight
TXAPA9 88,354,1987
inhalation/guinea pig lowest published toxic concentration: 580 µg/m3/6H/24W- intermittentLung, Thorax, or Respiration: Changes in lung weight

Blood: Changes in leukocyte (WBC) count

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
JEGPAY 54,171,1979

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.1 mg/m3 (thorac)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWJJOMDZ 14,199,1972

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 1 mg/m3 (dust)DTLVS* 3,60,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.2 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.2 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg/m3, MAY2011
Occupational Exposure Limit-FRANCEVME 0.2 mg/m3, fiber, FEB2006
Occupational Exposure Limit-GERMANYMAK 1.5 mg/m3, inhal, 2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 mg/m3, NOV2011
Occupational Exposure Limit-INDIAtime-weighted average 0.2 mg/m3, JAN1993
Occupational Exposure Limit-JAPANOccupational Exposure Limit 1 mg/m3 (resp. dust), 4 mg/m3 (total dust), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.2 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.2 mg/m3;short term exposure limit 0.6 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.2 mg/m3, JAN2002
Occupational Exposure Limit-SWEDENtime-weighted average 0.5 mg/m3, JUN2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 1.5 mg/m3, inhal, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 0.2 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.2 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 1 mg/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 2.5 mg/m3 (inhal. dust), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 1 mg/m3, raw dustCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 1 ppm, raw dustCFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)see 1910.1043CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 1 mg/m3, raw dustCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COTTON DUST-airlowest feasible concentrationNIOSH* DHHS #92-100,1992
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