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Registry of Toxic Effects of Chemical Substances (RTECS)

Cobalt, di-mu-carbonylhexacarbonyldi-, (Co-Co)

RTECS #

GG0300000

CAS #

10210-68-1; 90043-99-5

Updated

September 2013

Molecular Weight

341.94

Molecular Formula

C8Co2O8

Synonyms

Cobalt carbonyl
Cobalt carbonyl (ACGIH)
Cobalt octacarbonyl
Cobalt tetracarbonyl
Cobalt tetracarbonyl dimer
Dicobalt carbonyl
Dicobalt octacarbonyl
Di-mu-carbonylhexacarbonyldicobalt
Octacarbonyldicobalt

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): 26900 µg/m3/2HOlfaction: Other olfaction effects

Eye: Other eye effects

Lung, Thorax, or Respiration: Dyspnea
VRDEA5 (2),101,1969
inhalation/rat lethal concentration (50 percent kill): 165 mg/m3Lung, Thorax, or Respiration: Acute pulmonary edemaVRDEA5 (2),101,1969
oral/mouse lethal dose (50 percent kill): 378 mg/kgGISAAA 38(1),97,1973
oral/rat lethal dose (50 percent kill): 754 mg/kgGISAAA 38(1),97,1973

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 3468 mg/kg/23D- intermittentCardiac: Cardiomyopathy including infarction

Endocrine: Hyperglycemia

Blood: Pigmented or nucleated red blood cells
GISAAA 38(1),97,1973

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.02 mg(Co)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.1 mg(Co)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed animal carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 52,363,1991
International Agency for Research on Cancer (IARC)Cancer Review:Group 2BIMEMDT 52,363,1991
TOXICOLOGY REVIEWHBTME* ,511,2007

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.1 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.1 mg(Co)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.1 mg(Co)/m3, carc, MAY2011
Occupational Exposure Limit-FRANCEVME 0.1 mg/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.1 mg(Co)/m3, short term exposure limit 0.4 mg(Co)/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.1 mg(Co)/m3, NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Co)/m3, 2B carc, a1 sen, s2 sen, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.1 mg/m3, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.1 mg(Co)/m3, sen, JAN2002
Occupational Exposure Limit-PERUtime-weighted average 0.1 mg/m3, JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 mg(Co)/m3, carc 2, inhal, skin, sen, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.1 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.1 mg(Co)/m3, sen, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COBALT CARBONYL-air10H time-weighted average 0.1 mg/m3NIOSH* DHHS #95-121,1995

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
OSHA ANALYTICAL METHOD #ID-125G
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