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Registry of Toxic Effects of Chemical Substances (RTECS)

Cadmium

RTECS #

EU9800000

CAS #

7440-43-9

Updated

October 2017

Molecular Weight

112.40

Molecular Formula

Cd

Synonyms

C.I. 77180
Cadmium (ACGIH:OSHA)
Cadmium dust fume (OSHA)
Cadmium powder
Cadmium, elemental
Colloidal cadmium
Kadmium (German)

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisovary/hamster1 µmol/LCGCGBR 26,251,1980
DNA Damagelung/human10 µmol/LTOXID9 72,219,2003
DNA Damagefibroblast/mouse5 nmol/L/24HTOXID9 44,237,2005
DNA Damagelymphocyte/human250 µmol/L/1HTOXID9 12,430,2008
micronucleus testembryo/mouse6 µmol/LTIVIEQ 4,57,1990

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat 1124 µg/kg (1D male)Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)TXAPA9 41,194,1977
intraperitoneal/mouse 1686 µg/kg (7D pregnant)Reproductive: Specific developmental abnormalities: Central nervous systemTJADAB 28,39A,1983
intravenous/rat 1250 µg/kg (14D pregnant)Reproductive: Specific developmental abnormalities: Body wall

Reproductive: Specific developmental abnormalities: Urogenital system
JJATDK 1,264,1981
intravenous/rat 1250 µg/kg (9D pregnant)Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Eye, ear
JJATDK 1,264,1981
intravenous/rat 8 mg/kg (8-15D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)JJATDK 1,264,1981
oral/mouse 448 mg/kg (multigenerations)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Effects on embryo or fetus: Fetal death
AEHLAU 23,102,1971
oral/mouse 1700 mg/kg (8-12D pregnant)Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
TCMUD8 6,361,1986
oral/rat 155 mg/kg (13W male/13W pre-3W pregnant)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Behavioral
BECTA6 20,96,1978
oral/rat 220 mg/kg (1-22D pregnant)Reproductive: Other effects to embryo or fetusTOLED5 11,233,1982
oral/rat 21500 µg/kg (multigenerations)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on newborn: Germ cell effects (in offspring)
ENVRAL 22,466,1980
oral/rat 23 mg/kg (1-22D pregnant)Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow)PSEBAA 158,614,1978
oral/mouse 62 mg/kg (1D preg-10D after birth)Reproductive: Effects on newborn: Biochemical and metabolicTOXID9 228,77,2006
parenteral/hamster 2 mg/kg (8D pregnant)Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)TJADAB 31,52A,1985
subcutaneous/rat 250 µg/kg (19D pregnant)Reproductive: Effects on newborn: Biochemical and metabolicAPTOD9 19,A122,1980

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/woman lowest published toxic concentration: 129 µg/m3/20Y- continuousTumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
AJIMD8 10,153,1986
intramuscular/rat lowest published toxic dose: 40 mg/kg/4W- intermittentTumorigenic: Carcinogenic by RTECS criteria

Musculoskeletal: Tumors

Tumorigenic: Tumors at site of application
JEPTDQ 1(1),51,1977
intramuscular/rat toxic dose: 70 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease

Tumorigenic: Tumors at site of application
BJCAAI 18,124,1964
intramuscular/rat toxic dose: 63 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease

Tumorigenic: Tumors at site of application
NATUAS 193,592,1962
intramuscular/rat toxic dose: 45 mg/kg/4W- intermittentTumorigenic: Neoplastic by RTECS criteria

Musculoskeletal: Tumors

Tumorigenic: Tumors at site of application
NCIUS* PH43-64-886
subcutaneous/rat lowest published toxic dose: 3372 µg/kgTumorigenic: Carcinogenic by RTECS criteria

Tumorigenic: Tumors at site of application
ENVRAL 55,40,1991
unreported route/rat lowest published toxic dose: 1200 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Reproductive: Tumorigenic effects: Testicular tumors

Tumorigenic: Tumors at site of application
ZHYGAM 31,224,1985

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human Lowest published lethal concentration: 39 mg/m3/20MCardiac: Other changes

Vascular: Thromobosis distant from injection site

Lung, Thorax, or Respiration: Respiratory depression
AIHAAP 31,180,1970
inhalation/man lowest published toxic concentration: 88 µg/m3/8.6YKidney, Ureter, and Bladder: ProteinuriaAEHLAU 28,147,1974
inhalation/rat lethal concentration (50 percent kill): 25 mg/m3/30MLung, Thorax, or Respiration: DyspneaSAIGBL 16,212,1974
intraperitoneal/mouse lethal dose (50 percent kill): 5700 µg/kgTXAPA9 37,403,1976
intravenous/rabbit lowest published lethal dose: 5 mg/kgJOBSAK 35,693,1928
intravenous/rabbit lowest published toxic dose: 4 mg/kgEye: Other eye effectsTOXID9 66,206,2002
intravenous/rabbit lowest published lethal dose: 2.5 mg/kgLiver: Hepatitis (hepatocellular necrosis), zonal

Kidney, Ureter, and Bladder: Changes primarily in glomeruli

Blood: Granulocytopenia
TXAPA9 174,225,2001
intravenous/rabbit lowest published lethal dose: 3.5 mg/kgLiver: Multiple effects

Kidney, Ureter, and Bladder: Changes primarily in glomeruli

Blood: Granulocytopenia
TXAPA9 174,225,2001
oral/mouse lethal dose (50 percent kill): 890 mg/kgVCVN1* -,164,1988
oral/mouse lowest published toxic dose: 8 mg/kgMusculoskeletal: Osteoporosis

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects

Biochemical: Metabolism (intermediary): Other proteins
TOXID9 78,53,2004
oral/rabbit lowest published lethal dose: 70 mg/kgAMPMAR 34,127,1973
oral/rat lethal dose (50 percent kill): 2330 mg/kg85PDAD -,67,1978
parenteral/rat lowest published lethal dose: 5 mg/kgTOXID9 66,202,2002
skin/mouse lowest published lethal dose: 77.5 mg/kgTXAPA9 176,24,2001
subcutaneous/rabbit lowest published lethal dose: 6 mg/kgPROTA* -,-,1955
Tank with water/Daphnia lethal concentration (50 percent kill): 5 µg/L/48HTIVIEQ 31,125,1995
Tank with water/Trout lowest published toxic concentration: 0.4 mg(Cd)/L/7DEndocrine: Evidence of thyroid hyperfunction

Endocrine: Adrenal cortex hyperplasia
TIVIEQ 35,157,1996
Tank with water/Trout lowest published toxic concentration: 0.4 mg(Cd)/L/2HEndocrine: Evidence of thyroid hyperfunction

Endocrine: Adrenal cortex hyperplasia

Endocrine: Hyperglycemia
TIVIEQ 35,157,1996
unreported route/man lowest published lethal dose: 15 mg/kg85DCAI 2,73,1970
unreported route/mouse lethal dose (50 percent kill): 890 mg/kgGTPZAB 22(5),6,1978
unreported route/rat lethal dose (50 percent kill): 1140 mg/kgGTPZAB 22(5),6,1978

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat : 15 mg/kg/15D- intermittentCardiac: Other changes

Vascular: BP elevation not characterized in autonomic section

Biochemical: Metabolism (intermediary): Lipids including transport
TOXID9 227,15,2006
multiple/man lowest published toxic dose: 0.0355 gm/kg/30Y- intermittentKidney, Ureter, and Bladder: Proteinuria

Kidney, Ureter, and Bladder: Other changes in urine composition
JAPTO* 22,431,2002
multiple/woman lowest published toxic dose: 0.0498 gm/kg/30Y- intermittentKidney, Ureter, and Bladder: Other changes in urine compositionJAPTO* 22,431,2002
oral/human lowest published toxic dose: 53.6 mg/kg/50Y- continuousKidney, Ureter, and Bladder: Proteinuria

Kidney, Ureter, and Bladder: Other changes
JJATDK 22,431,2002
oral/mouse lowest published toxic dose: 504 mg/kg/6W- continuousReproductive: Paternal effects: Testes, epididymis, sperm ductTXAPA9 197,269,2004
oral/mouse lowest published toxic dose: 210 mg/kg/15W- continuousKidney, Ureter, and Bladder: ProteinuriaTOXID9 66,80,2002
oral/mouse lowest published toxic dose: 1302 µg/kg/31W- continuousBlood: Changes in spleen

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Immunological Including Allergic: Autoimmune (multiple organ involvement)
TOXID9 66,80,2002
oral/pig lowest published toxic dose: 21880 mg/kg/78W- continuousVascular: BP elevation not characterized in autonomic sectionTOXID9 13,162,1993
oral/rat lowest published toxic dose: 546 mg/kg/26W- continuousBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
TOXID9 2,52,1982
oral/rat lowest published toxic dose: 1512 mg/kg/48W- continuousLiver: Other changes

Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Changes in: Other metals
TOLED5 5,105,1980
oral/rat lowest published toxic dose: 37.5 mg/kg/30D- continuousKidney, Ureter, and Bladder: Other changes

Blood: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
TOXID9 72,17,2003
oral/rat lowest published toxic dose: 3780 mg/kg/9W- continuousImmunological Including Allergic: Autoimmune (multiple organ involvement)TOXID9 66,80,2002
oral/rat lowest published toxic dose: 150 mg/kg/30D- continuousEye: Other eye effects

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases

Biochemical: Metabolism (intermediary): Effect on Na-K pump
RJENT* 1,204,2007
oral/rat lowest published toxic dose: 420 mg/kg/12W- continuousBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
FCTOD7 42,429,2004
oral/woman lowest published toxic dose: 75 mg/kg/40Y- continuousKidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Other changes
JJATDK 22,431,2002
subcutaneous/rat lowest published toxic dose: 15 mg/kg/5W- intermittentKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Kidney, Ureter, and Bladder: Proteinuria
TOXID9 72,349,2003
subcutaneous/rat lowest published toxic dose: 15 mg/kg/5W- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Other changes
TOXID9 -,77,2008
subcutaneous/rat lowest published toxic dose: 24 mg/kg/8W- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Nutritional and Gross Metabolic: Changes in: Other metals

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
TOXID9 -,77,2008
subcutaneous/rat lowest published toxic dose: 30 mg/kg/10W- intermittentKidney, Ureter, and Bladder: Proteinuria

Kidney, Ureter, and Bladder: Other changes in urine composition

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
TOXID9 -,77,2008

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.01 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Suspected human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 2,74,1973
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 11,39,1976
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 58,119,1993
International Agency for Research on Cancer (IARC)Cancer Review:Human Limited EvidenceIMSUDL 7,139,1987
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 58,119,1993
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 100C,141,2012
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 100C,141,2012
International Agency for Research on Cancer (IARC)Cancer Review:Group 1IMEMDT 58,119,1993
International Agency for Research on Cancer (IARC)Cancer Review:Group 1IMEMDT 100C,141,2012
TOXICOLOGY REVIEWTRBMAV 33,85,1975
TOXICOLOGY REVIEWJDSCAE 58,1767,1975
TOXICOLOGY REVIEWJFDSAZ 39,321,1974
TOXICOLOGY REVIEWAMBOCX 3,55,1974
TOXICOLOGY REVIEWQURBAW 7,75,1974
TOXICOLOGY REVIEWAEMBAP 40,239,1973
TOXICOLOGY REVIEWNTIS** PB221-198
TOXICOLOGY REVIEWKOTTAM 11,1300,1975
TOXICOLOGY REVIEWFOREAE 7,313,1942
TOXICOLOGY REVIEWSTEVA8 2,341,1974
TOXICOLOGY REVIEWFCTXAV 9,105,1971
TOXICOLOGY REVIEWAJMEAZ 38,409,1965
TOXICOLOGY REVIEWENVRAL 4,71,1971
TOXICOLOGY REVIEW85CVA2 5,63,1970
TOXICOLOGY REVIEWPEXTAR 12,102,1969
TOXICOLOGY REVIEWPDTNBH 6,204,1977
TOXICOLOGY REVIEWBNYMAM 54,413,1978
TOXICOLOGY REVIEWAMTODM 3,209,1977
TOXICOLOGY REVIEWGSAMAQ 123,109,1971
TOXICOLOGY REVIEW49DXAV -,57,1983
TOXICOLOGY REVIEW43QNAO 2,743,1981
TOXICOLOGY REVIEWCREOH* 42,93,2002
TOXICOLOGY REVIEWMUREAV 540,19,2003
TOXICOLOGY REVIEWTOLED5 127,63,2002
TOXICOLOGY REVIEWTOLED5 134,17,2002
TOXICOLOGY REVIEWTOLED5 140-141,53,2003
TOXICOLOGY REVIEWTOLED5 140-141,161,2003
TOXICOLOGY REVIEWTOLED5 140-141,311,2003
TOXICOLOGY REVIEWMAERE* 51,247,2001
TOXICOLOGY REVIEWMUREAV 567,109,2004
TOXICOLOGY REVIEWMAERE* 52,173,2001
TOXICOLOGY REVIEWTXAPA9 197,144,2004
TOXICOLOGY REVIEWCRTXB2 33,215,2003
TOXICOLOGY REVIEWTXAPA9 207,179,2005
TOXICOLOGY REVIEWREPTED 22,196,2006
TOXICOLOGY REVIEWREPTED 22,164,2006
TOXICOLOGY REVIEWMUREAV 613,17,2006
TOXICOLOGY REVIEWNRTXDN 27,429,2006
TOXICOLOGY REVIEWMUREAV 613,76,2006
TOXICOLOGY REVIEWDIMON* 46,551,2000
TOXICOLOGY REVIEWENTOX* -,375,2005
TOXICOLOGY REVIEWJJATDK 26,191,2006
TOXICOLOGY REVIEWHETOEA 25,67,2006
TOXICOLOGY REVIEWTOPADD 32(Suppl. 2),71,2004
TOXICOLOGY REVIEWJTEHD6 6,227,2003
TOXICOLOGY REVIEWMUREAV 533,107,2003
TOXICOLOGY REVIEWREPTED 23,260,2007
TOXICOLOGY REVIEWMUREAV 544,305,2003
TOXICOLOGY REVIEWREPTED 23,297,2007
TOXICOLOGY REVIEWJTPAE7 19,1,2006
TOXICOLOGY REVIEWHBTME* ,445,2007
TOXICOLOGY REVIEWMUREAV 544,313,2003
TOXICOLOGY REVIEWHTOPA* 1,701,2002
TOXICOLOGY REVIEWITODC* -,355,2004
TOXICOLOGY REVIEWHUTOX* -,515,1996
TOXICOLOGY REVIEWHTOPA* 1,501,2002
TOXICOLOGY REVIEWFCTOD7 46,813,2008
TOXICOLOGY REVIEWMUREAV 674,3,2009
TOXICOLOGY REVIEWMUREAV 674,36,2009
TOXICOLOGY REVIEWMUREAV 674,73,2009
TOXICOLOGY REVIEWMUREAV 636,144,2007
TOXICOLOGY REVIEWREPTED 27,1,2009
TOXICOLOGY REVIEWMUREAV 681,80,2009
TOXICOLOGY REVIEWTXAPA9 243,167,2010
TOXICOLOGY REVIEWNETEEC 32,4,2010
TOXICOLOGY REVIEWNTAPM* -,265,1995
TOXICOLOGY REVIEWNTAPM* -,629,1995
TOXICOLOGY REVIEWNTAPM* -,727,1995
TOXICOLOGY REVIEWMUREAV 705,130,2010
TOXICOLOGY REVIEWTOLED5 192,45,2010
TOXICOLOGY REVIEWMUTAEX 26,205,2011
TOXICOLOGY REVIEWMUREAV 714,105,2011
TOXICOLOGY REVIEWMUREAV 717,46,2011
TOXICOLOGY REVIEWREPTED 33,269,2012
TOXICOLOGY REVIEWREPTED 35,165,2013
TOXICOLOGY REVIEWMUREAV 746,113,2012
TOXICOLOGY REVIEWREPTED 34,298,2012
TOXICOLOGY REVIEWTXAPA9 254,86,2011
TOXICOLOGY REVIEWTXAPA9 248,71,2010
TOXICOLOGY REVIEWEMMUEG 54,589,2013
TOXICOLOGY REVIEWEMMUEG 54,500,2013
TOXICOLOGY REVIEWMUREAV 760,1,2014
TOXICOLOGY REVIEWMUREAV 759,27,2014
TOXICOLOGY REVIEWEMMUEG 55,171,2014
TOXICOLOGY REVIEWEMMUEG 55,278,2014
TOXICOLOGY REVIEWEMMUEG 55,155,2014
TOXICOLOGY REVIEWMUREAV 764-765,10,2014
TOXICOLOGY REVIEWEMMUEG 54,468,2013
TOXICOLOGY REVIEWREPTED 49,117,2014
TOXICOLOGY REVIEWFCTOD7 86,298,2015
TOXICOLOGY REVIEWTXCYAC 313,3,2013
TOXICOLOGY REVIEWFCTOD7 94,93,2016
TOXICOLOGY REVIEWMUREAV 770,119,I2
TOXICOLOGY REVIEWMUREAV 770,140,I2

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.2 mg/m3DTLVS* 3,35,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.05 mg/m3, JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.01 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.002 mg/m3 (resp. dust), Carcinogen, MAR2002
Occupational Exposure Limit-BELGIUMtime-weighted average 0.01 mg/m3 (inhal. dust), Carcinogen, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.005 mg/m3 (fume, dust), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.02 mg/m3, skin, NOV2011
Occupational Exposure Limit-FRANCEVME 0.05 mg/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.015 mg/m3, short term exposure limit 0.06 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.01 mg/m3 (resp. dust), carc, NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg/m3, 1 carc, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.05 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.01 mg/m3 (total dust), 2004
Occupational Exposure Limit-MEXICOtime-weighted average 0.002 mg/m3 (inhalable), 2004
Occupational Exposure Limit-MEXICOtime-weighted average 0.002 mg(Cd)/m3 (inhalable), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.01 mg(Cd)/m3 (inspirable dust), JAN2002
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.002 mg(Cd)/m3 (respirable dust), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.05 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0.01 mg/m3 (inhal), 0.002 mg/m3 (resp), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) dust 0.04 mg/m3, MAC(short term exposure limit) dust 0.2 mg/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) fume 0.02 mg/m3, MAC(short term exposure limit) fume 0.05 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.01 mg/m3, short term exposure limit 0.05 mg/m3, Carcinogen, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 0.02 mg/m3(total dust);time-weighted average 0.005 mg/m3(resp. dust), Carcinogen, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.015 mg/m3, carc 2, inhal, skin, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 0.2 mg/m3, short term exposure limit 0.5 mg/m3, JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.005 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.2 mg/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.2 mg/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.025 mg/m3, carc, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)see Code of Federal Regulations (CFR) 29,1926.1127CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.2 mg(Cd)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)see Code of Federal Regulations (CFR) 29,1910.1027CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)see Code of Federal Regulations (CFR) 29,1915.1027CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CADMIUM, dust and fume-airCarcinogen lowest feasible conc.NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code T0608; Number of Industries 2; Total Number of Facilities 25; Number of Occupations 3; Total Number of Employees Exposed 335; Total Number of Female Employees Exposed 22
National Occupational Exposure Survey 1983Hazard Code X2776; Number of Industries 5; Total Number of Facilities 248; Number of Occupations 6; Total Number of Employees Exposed 3893; Total Number of Female Employees Exposed 1887
National Occupational Exposure Survey 1983Hazard Code X5979; Number of Industries 2; Total Number of Facilities 95; Number of Occupations 2; Total Number of Employees Exposed 486
National Occupational Exposure Survey 1983Hazard Code 15570; Number of Industries 77; Total Number of Facilities 4811; Number of Occupations 64; Total Number of Employees Exposed 88968; Total Number of Female Employees Exposed 14541
National Occupational Hazard Survey 1974Hazard Code T0608; Number of Industries 1; Total Number of Facilities 48; Number of Occupations 1; Total Number of Employees Exposed 96
National Occupational Hazard Survey 1974Hazard Code 15570; Number of Industries 41; Total Number of Facilities 1256; Number of Occupations 50; Total Number of Employees Exposed 14717

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/166621)
EPA GENETOX PROGRAM 1988, Inconclusive: In vivo cytogenetics-human lymphocyte
EPA GENETOX PROGRAM 1988, Positive/limited: Carcinogenicity-mouse/rat
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Cadmium and compounds, as Cd, 7048
NIOSH Analytical Method, 1994: Elements by ICP, 7300
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
NIOSH Analytical Method, 1994: Metals in urine, 8310
NIOSH CURRENT INTELLIGENCE BULLETIN 42, 1984
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen
On EPA IRIS database
OSHA ANALYTICAL METHOD #ID189
OSHA ANALYTICAL METHOD #ID206
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