Notice of Funding Opportunity PS-24-042: A Bridge to Adherence: Long-Acting Antiretroviral Therapy for People with HIV Released from Prison

This website is designed to:

  • Support the application process for health departments applying for Notice of Funding Opportunity (NOFO) PS-24-042, and
  • Provide a forum for the dissemination of important information to potential applicants.

This Notice of Funding Opportunity announcement is available at The view the entire announcement go to and click on the “Search Grants” tab. Then enter  “RFA-PS-24-042” into the “Basic Search Criteria-Opportunity Announcement. To learn more about the CDC application process, visit How to Apply for Grants webpage.

Executive Summary

This Notice of Funding Opportunity (NOFO) is designed to understand the feasibility and acceptability of providing long-acting injectable antiretroviral therapy (LAI-ART) to incarcerated persons with HIV who are soon to be released from state prison facilities. The transition period from incarceration to the community is a particularly critical time for people with HIV (PWH) and ensuring continuity of care and treatment is vital. PWH living in prison facilities are often released to the community lacking support for ongoing HIV care. There is a paucity of programs for this population demonstrating effectiveness with retention in care and maintaining sustained HIV viral suppression after release. The use of LAI-ART prior to and at the time of release from prison may improve adherence to HIV treatment, retention in care, and maintenance of viral load suppression among persons reentering the community. The intervention entails pre-release navigation, counseling for PWH about the use of LAI-ART, and a post-release care plan including linkage to a medical provider in the community to ensure continuity of HIV care. The ultimate goal is to support the development and implementation of effective, sustainable, replicable LAI-ART programs. Applied qualitative and quantitative research resulting from this funding is expected to strengthen adherence to ART and is aligned with the National HIV/AIDS Strategy (NHAS) and the Ending the HIV Epidemic in the U.S. (EHE) initiative “Treat” Pillar.


The purpose of this NOFO is to support research on long-acting injectable (LAI) antiretroviral therapy (ART) by implementing and evaluating LAI-ART use among people soon to be released from prisons to the community and the effects of such use on the achievement and maintenance of HIV care continuum metrics. Recipients of this NOFO will conduct qualitative and quantitative research resulting in data describing real-world LAI-ART use in an era of multiple HIV treatment modalities.

Application is due on 02/29/2024. Please direct questions to Jocelyn Patterson Mosley, MPH, MA, Scientific/Research Contact, 404-639-6437.