Notice of Funding Opportunity PS22-2210: Mass Mailing of HIV Self-Tests to Persons Disproportionately Affected by HIV in the U.S.

This website is designed to:

  • Support the application process for Notice of Funding Opportunity (NOFO) PS22-2210, and
  • Provide a forum for the dissemination of important information to potential applicants.

Access the Notice of Funding Opportunity

Executive Summary

The use of HIV self-tests (HIVSTs) is one mechanism to increase awareness of ones HIV status. This project will increase awareness of HIV infections in the U.S. among populations disproportionately affected by HIV. The project supports the National HIV/AIDS Strategy (NHAS) and Ending the HIV Epidemic in the U.S. (EHE) initiative goal of increasing the proportion of people with HIV who have received a diagnosis. To achieve this, the project will distribute at least 875,000 HIVSTs over 5 years through direct-to-consumer digital marketing in both English and Spanish. The project has two strategies. 1) The adaptation of the recipient’s own existing HIVST distribution program which will include the optimization of a system of procurement, storage, processing orders and distribution of at least 175,000 HIVSTs per year directly to consumers in the U.S. and Puerto Rico. Adaptation will also require ensuring the pairing of their existing HIVST distribution program to match the look and feel of CDC’s Let’s Stop HIV Together marketing campaigns for men who have sex with men (MSM), transgender women (TGW), and Black cis-gender women, in both English and Spanish. 2) Purchase and distribute HIVSTs, meet virtually with CDC regularly (weekly) to discuss routinely collected program monitoring and evaluation data, and implement CDC revised marketing strategies throughout the project.


This NOFO will optimize the recipient’s existing web-based ordering portal and distribution program to provide at least 875,000 HIVSTs to U.S. populations disproportionately affected by HIV. The NOFO will maximize distribution of HIVSTs to MSM, TGW and Black cis-gender women via digital and traditional marketing strategies from CDC’s Let’s Stop HIV Together campaigns, predominately in EHE jurisdictions. The use of the program’s HIVSTs and referrals will increase awareness of HIV infection, prevent new infections, decrease HIV transmission, and improve overall health and well-being of participants.