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Photomicrographs Showing Histopathological Features Less Commonly Seen in Cases of HPS

Images courtesy of Sherif R. Zaki, M.D., Ph.D.

less commonly seen histopathological features in cases of HPS
  • Lung showing extensive interstitial and alveolar fibrosis. Noe the increased interstitial cellularity with numerous fibroblasts. Original magnification: x50
  • Patchy areas of alveolar septal thickening and prominent hyaline membranes. Original magnification: x50
  • Higher magnification showing typical dense laminated hyaline membranes. Original magnification: x100
  • Alveolar septum showing prominent type II pneumocyte proliferation. Original magnification: x158
  • Abundant polymorphonuclear leukocytes fill alveolar spaces with focal destruction of alveolar septa. Original magnification: x50
  • Higher power magnification showing the antraalveolar exudate composed mainly of polymorphonuclear leukocytes, red blood cells, and fibrin. Original magnification: x158
  • Page last reviewed: May 17, 2011
  • Page last updated: May 17, 2011 The U.S. Government's Official Web PortalDepartment of Health and Human Services
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