For Healthcare Providers

Epstein-Barr virus (EBV) can cause illnesses and complications aside from infectious mononucleosis. People with weakened immune systems may develop more severe symptoms and complications from EBV infection. They may also have more severe illness caused by EBV infection.

Nervous System

EBV infection can affect a person’s brain, spinal cord, and nerves.

It can cause conditions such as—

Hematological System

EBV infection can affect a person’s blood and bone marrow. The virus can cause the body to produce an excessive number of white blood cells called lymphocytes (lymphocytosis).

EBV can also weaken the immune system, making it more difficult for the body to fight infection.

Examples of some of these conditions include—

  • Neutropenia with secondary infections
  • Hemophagocytic syndrome (hemophagocytic lymphohistiocytosis)
  • Acquired hypogammaglobulinemia
  • X-linked lymphoproliferative disease

Other Conditions

EBV infection can also cause—

Cancers associated with EBV infection include—

Complications of EBV infection include—

Page last reviewed: May 8, 2018