In addition to A. phagocytophilum, the blacklegged tick also transmits several other pathogens in certain geographic areas, including:
- Borrelia burgdorferi (the causative agent of Lyme disease),
- Babesia microti (the primary cause of human babesiosis),
- Borrelia mayonii (a newly discovered cause of borreliosis),
- Borrelia miyamotoi (a cause of tickborne relapsing fever)
- Powassan virus (cause of Powassan virus disease), and
- Ehrlichia muris eauclairensis
Risk of coinfection
- Anaplasma coinfection with non-rickettsial pathogens has been reported in <10% of patients.
- Rash is rarely reported (<10% of cases) in patients with anaplasmosis. The presence of a rash might indicate that the patient has a coinfection with Lyme disease, or another tickborne disease.
For more in-depth information about signs and symptoms of anaplasmosis, see: Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis — United States: A Practical Guide for Health Care and Public Health Professionals (2016) Cdc-pdf[PDF – 48 pages]