Reporting and Surveillance
CDC is investigating a possible association between pediatric hepatitis and adenovirus infection. Visit CDC’s NCIRD site for information about the investigation: Children with Acute Hepatitis of Unknown Cause.
Adenovirus infections are not nationally notifiable in the United States. Adenovirus infections and outbreaks may not be reported, even if they are diagnosed.
CDC tracks seasonal trends in adenovirus-associated illness through two surveillance systems. Adenovirus typing results are tracked by the National Adenovirus Type Reporting System (NATRS) and untyped adenovirus results are tracked by the National Respiratory and Enteric Virus Surveillance System (NREVSS).
NATRS is a passive, laboratory-based surveillance system that collects limited clinical, demographic, and laboratory data on typed human adenovirus specimens. NATRS was implemented in 2014 to monitor type-specific human adenovirus temporal and geographic circulation patterns.
NREVSS is a passive, laboratory-based surveillance system that has monitored adenovirus laboratory results since 1989. Each week, laboratories report the number of weekly aggregate adenovirus tests performed and the number of tests positive for adenovirus by specimen type, location, and the week of specimen collection. Serotyping, demographic, and clinical data are not collected in NREVSS.
CDC. Human Adenovirus Surveillance — United States, 2003-2016. MMWR Morb Mortal Wkly Rep. 2017;66(39):1039-42.