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Adenovirus infections can be identified using antigen detection, polymerase chain reaction, virus isolation, and serology. Adenovirus typing is usually done by hemagglutination-inhibition and/or neutralization with type-specific antisera or by molecular methods.

Even if a person has adenovirus infection, it does not necessarily mean it is causing the person’s particular illness. A person can shed the virus for months or longer and not have symptoms.

Health professionals should

  • consider adenoviruses as possible causes of upper respiratory infection, lower respiratory infection such as pneumonia, and conjunctivitis (individual cases or outbreaks)
  • report unusual clusters (e.g., respiratory, conjunctivitis) caused by adenoviruses to the state or local health department

For more information, see