Outbreaks of adenovirus infection can occur throughout the year. They are usually associated with respiratory illnesses or conjunctivitis.
Reported sporadic cases and outbreaks of adenovirus have included:
- Adenovirus types 3, 4 and 7, which are most commonly associated with acute respiratory disease
- Adenovirus type 14, which since 2007 has been associated with outbreaks of acute respiratory illness among U.S. military recruits and the general public
- Adenovirus types 8, 19, 37, 53, and 54, which can cause epidemic keratoconjunctivitis
- Enteric adenovirus types 40 and 41, which cause gastroenteritis, usually in children
- Some adenoviruses (e.g., 4 and 7) that spread in bodies of water such as small lakes or swimming pools without adequate chlorine and can cause outbreaks of febrile disease with conjunctivitis
Health Professionals should
- Consider adenoviruses as possible causes of upper respiratory illness, and lower respiratory illness such as pneumonia
- Report unusual clusters of illness (e.g., respiratory, conjunctivitis) potentially caused by adenoviruses to the state or local health department
- Clinical Overview of Adenoviruses
- CDC. Notes from the Field: Fatalities Associated with Human Adenovirus Type 7 at a Substance Abuse Rehabilitation Facility — New Jersey, 2017. MMWR. 2018;67:371–372.
- CDC. Adenovirus-associated epidemic keratoconjunctivitis outbreaks — four states, 2008–2010. MMWR. 2013;62(32);637-41.
- James L, Vernon M, Jones R, et al. Outbreak of Human Adenovirus Type 3 Infection in a Pediatric Long-Term Care Facility—Illinois, 2005External. Clinical Infectious Diseases. Volume 45, Issue 4, 15 August 2007, Pages 416–420.
Page last reviewed: April 26, 2018