Outbreaks of adenovirus infection can occur throughout the year. They are usually associated with respiratory illnesses or conjunctivitis.

Reported sporadic cases and outbreaks of adenovirus have included:

  • Adenovirus types 3, 4 and 7, which are most commonly associated with acute respiratory disease
  • Adenovirus type 14, which since 2007 has been associated with outbreaks of acute respiratory illness among U.S. military recruits and the general public
  • Adenovirus types 8, 19, 37, 53, and 54, which can cause epidemic keratoconjunctivitis
  • Enteric adenovirus types 40 and 41, which cause gastroenteritis, usually in children
  • Some adenoviruses (e.g., 4 and 7) that spread in bodies of water such as small lakes or swimming pools without adequate chlorine and can cause outbreaks of febrile disease with conjunctivitis

Health Professionals should

  • Consider adenoviruses as possible causes of upper respiratory illness, and lower respiratory illness such as pneumonia
  • Report unusual clusters of illness (e.g., respiratory, conjunctivitis) potentially caused by adenoviruses to the state or local health department