Complications of SCD: Pulmonary Hypertension (High Blood Pressure in the Lungs)

At a glance

Sickle cell disease (SCD) is a group of inherited blood disorders associated with severe pain and complications that can affect the entire body. This page provides information on SCD and pulmonary hypertension (high blood pressure in the lungs).

A woman holding her chest.


People with SCD are at greater risk than the general population for high blood pressure in the lungs, which can be life-threatening.


Some signs and symptoms of high blood pressure in the lungs can include:

  • Difficulty breathing
  • Fatigue
  • Chest discomfort or pain
  • Swelling of the ankles, legs, or abdomen (belly)
  • Light-headedness or dizziness