At a glance
Sickle cell disease (SCD) is a group of inherited blood disorders associated with severe pain and complications that can affect the entire body. This page provides information on SCD and pulmonary hypertension (high blood pressure in the lungs).

Overview
People with SCD are at greater risk than the general population for high blood pressure in the lungs, which can be life-threatening.
Symptoms
Some signs and symptoms of high blood pressure in the lungs can include:
- Difficulty breathing
- Fatigue
- Chest discomfort or pain
- Swelling of the ankles, legs, or abdomen (belly)
- Light-headedness or dizziness
Resources
CDC resources
Other resources
Pulmonary Hypertension | National Heart, Lung, and Blood Institute
Pulmonary Hypertension | National Library of Medicine, MedlinePlus
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