Complications of SCD: Leg Ulcers

For Everyone

At a glance

Sickle cell disease (SCD) is a group of inherited blood disorders associated with severe pain and complications that can affect the entire body. This page provides information on SCD and leg ulcers.

Leg being wrapped with gauze

Overview

Poor circulation of blood in the leg can lead to painful leg ulcers, usually on the lower part of the leg. Leg ulcers happen more often in males than in females. They usually appear in people aged 10 to 50 years. A combination of factors can cause ulcers, including:

  • Trauma
  • Infection
  • Inflammation (swelling)
  • Poor blood flow in the smallest blood vessels of the legs

Symptoms

Common symptoms include:

  • Open sores
  • Pain in the affected area
  • Pus or discharge in the affected area
  • Swelling
  • An itchy or burning feeling
Content Source
National Center on Birth Defects and Developmental Disabilities (NCBDDD)
About This Page
Published: May 15, 2024
Updated: May 14, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 7, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.