Guidelines and Recommendations for Treating and Managing Health Conditions during Pregnancy

Doctor consulting with patient presenting results on a tablet

Listed below are selected guidelines and recommendations for treating and managing various health conditions during pregnancy. This information is not comprehensive and does not include all treatments or methods.

Asthma

Asthma controller therapy during pregnancy
Am J Obstet Gynecol. 2005; 192(2): 369-380.
Gluck JC, Gluck PA.
[Read summary]

Managing asthma during pregnancy: recommendations for pharmacologic treatment–Update 2004
These NIH recommendations, updated during 2004, provide guidance on medication treatment for pregnant women with asthma.
[Read recommendations]

Depression

Management of Depression During Pregnancy: A Report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists
Obstet Gynecol. 2009; 114: 703-713
Yonkers KA, Wisner KL, Stewart DE; et. al.
[Read guidelines]

ACOG Practice Bulletin No. 92: Use of psychiatric medications during pregnancy and lactation
Obstet Gynecol. 2008; 111: 1001–1020.
ACOG Committee on Practice Bulletins—Obstetrics.
[ACOG members can access the bulletin here]

ACOG Committee Opinion No. 757: Screening for perinatal depression
Obstet Gynecol 2018;132:e208–12.
American College of Obstetricians and Gynecologists.
[Read recommendations]

Epilepsy

Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence based review): Teratogenesis and perinatal outcomes
Neurology. 2009; 73: 133-141.
Harden CL, Meador KJ, Pennell PB, et al.
[Read recommendations]

Heart Disease

ACOG Practice Bulletin No. 212: Pregnancy and Heart Disease
Obstet Gynecol 2019;133:e320–56.
American College of Obstetricians and Gynecologists.
[Read recommendations]

Management of Pregnancy in Patients With Complex Congenital Heart Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association
Circulation 2017;135:e50-87.
Canobbio MM, Warnes CA, Aboulhosn J, et al., on behalf of the American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; Council on Functional Genomics and Translational Biology; and Council on Quality of Care and Outcomes Research.
[Read guidelines]

Infections (e.g., Colds, Urinary Tract Infections, Human Immunodeficiency Virus [HIV])

ACOG Practice Advisory: COVID-19 Vaccination Considerations for Obstetric–Gynecologic Care
[Read recommendations]

Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infection and Interventions to Reduce Perinatal HIV Transmission in the United States
Panel on Treatment of Pregnant Women with HIV Infection and Prevention of Perinatal Transmission. 2018.
[Read recommendations [PDF 3.28MB – 322 pages]]

Preconception care for HIV-infected women
New York (NY): New York State Department of Health; 2010 Jul. 15.
[Read guidelines]

U.S. Public Health Service Task Force recommendations for use–of antiretroviral drugs in pregnant HIV-1–infected women for maternal health and interventions to reduce perinatal HIV-1 transmission in the United States
[Read recommendations]

Updated recommendations for antimicrobial prophylaxis among asymptomatic pregnant women after exposure to Bacillus anthracis
MMWR Morb Mortal Wkly Rep. 2001;50(43):960.
[Read recommendations]

ACOG Committee Opinion No. 741: Maternal Immunizations
Obstet Gynecol. 2018; 131: 214-217.
[Read summary]

Pregnant Women & Influenza (Flu)
[Read recommendations]

Vaccination Information for Women Who are Pregnant or Breastfeeding
[Read guidelines]

CDC’s Recommendations for Hepatitis C Screening During Every Pregnancy
[Test for Hepatitis C During Every Pregnancy | CDC]

CDC’s Recommendations for STIs during Pregnancy
[Pregnant Women (cdc.gov)]

Nausea and Vomiting

ACOG Practice Bulletin No. 189: Nausea and Vomiting Of Pregnancy
Obstet Gynecol. 2018;131:15-30.
[Read recommendations]

Pain

Clinical Guidance for Treating Pregnant and Parenting Women With Opioid Use Disorder and Their Infants
SAMHSA. 2018; HHS Publication No. (SMA) 18-5054
[Read guidelines]

CDC Guidelines for Prescribing Opioids for Chronic Pain—United States, 2016
MMWR Recomm Rep 2016;65(No. RR-1):1–4
Dowell D, Haegerich TM, Chou R.
[Read guidelines]

ACOG Committee Opinion No. 711: Opioid Use and Opioid Use Disorder in Pregnancy
Obstet Gynecol. 2017;130:81-94.
[Read summary]

Thyroid Disorders

ACOG Practice Bulletin No. 148: Thyroid Disease in Pregnancy
Obstet Gynecol. 2015; 125(4):996-1005.
[Read recommendations]

Additional Resources

Many organizations are committed to understanding more about medicines and pregnancy and providing helpful resources for women and healthcare providers.

Food and Drug Administration (FDA)
FDA’s site contains information about taking medicines during pregnancy:

LactMed
Hosted by the National Library of Medicine, LactMed is a database that contains information about specific medicines, ways they might affect breastfeeding mothers and their babies, and potential alternatives to consider, if needed.

March of Dimes
This webpage provides information related to the use of medicines and herbal products during pregnancy.

MotherToBaby
MotherToBaby provides information and fact sheets, in English and Spanish, on the risks and safety of taking specific medicines during pregnancy and breastfeeding. To speak with a MotherToBaby counselor about the safety of a medicine you have taken or you are thinking of taking, call 1-866-626-6847. This service is free and confidential.

Office on Women’s Health, U.S. Department of Health and Human Services
This website and toll-free call center provide free, reliable health information for women everywhere. The site contains a database of resources and includes topic areas, such as pregnancy and medicine.

Page last reviewed: September 20, 2022