Publications, Data, & Statistics

National Outbreak of Acanthamoeba Keratitis Associated with Use of a Contact Lens Solution, United States. Cdc-pdf[PDF – 7 pages] (Vol. 15, No. 8 / August 15, 2009)

• CDC. Investigational Drug Available Directly from CDC for the Treatment of Infections with Free-Living Amebae. MMWR Morb Mortal Wkly Rep. 2013;62(33):666.
• CDC. Acanthamoeba Keratitis — Multiple States, 2005-2007. MMWR Morb Mortal Wkly Rep. 2007;56(Dispatch):1-3.
• CDC. Acanthamoeba Keratitis in Soft-Contact-Lens Wearers. MMWR Morb Mortal Wkly Rep. 1987;36(25):397-8, 403-4.
• CDC. Acanthamoeba Keratitis Associated with Contact Lenses — United States. MMWR Morb Mortal Wkly Rep. 1986;35(25):405-8.

• Yoder JS, Verani J, Heidman N, Hoppe-Bauer J, Alfonso EC, Miller D, Jones DB, Bruckner D, Langston R, Jeng BH, Joslin CE, Tu E, Colby K, Vetter E, Ritterband D, Mathers W, Kowalski RP, Acharya NR, Limaye AP, Leiter C, Roy S, Lorick S, Roberts J, Beach MJ. Acanthamoeba keratitis: The Persistence of Cases Following a Multistate Outbreak.External Ophthalmic Epidemiol. 2012;19(4):221-5.
• Johnston SP, Sriram R, Qvarnstrom Y, Roy S, Verani J, Yoder JS, Lorick S, Roberts J, Beach MJ, Visvesvara G. Resistance of Acanthamoeba cysts to disinfection in multiple contact lens solutions. J Clin Micro 2009;47:2040-5.
• Awwad ST, Petroll WM, McCulley JP, Cavanagh HD. Updates in Acanthamoeba keratitis. Eye Contact Lens. 2007;33:1-8.
• Ibrahim YW, Boase DL, Cree IA. Factors affecting the epidemiology of Acanthamoeba keratitis. Ophthalmic Epidemiol. 2007 Mar-Apr;14:53-60.
• Joslin CE, Elmer YT, McMahon TT, Passaro DJ, Stayner LT, Sugar J. Epidemiological characteristics of a Chicago-area Acanthamoeba keratitis outbreak. Am J Ophthalmol. 2006 Aug;142(2):212-17.
• Parmar DN, Awwad ST, Petroll WM, Bowman RW, McCulley JP, Cavanagh HD. Tandem scanning confocal corneal microscopy in the diagnosis of suspected Acanthamoeba keratitis. Ophthalmology. 2006;113:538-47.
• Yu HS, Kong HH, Kim SY, Hahn YH, Hahn TW, Chung DI. Laboratory investigation of Acanthamoeba lugdunensis from patients with keratitis. Invest Ophthalmol Vis Sci. 2004;45:1418-26.
• Driebe WT Jr. Present status of contact lens-induced corneal infections. Ophthalmol Clin North Am. 2003;16:485-94.
• Hurt M, Niederkorn J, Alizadeh H. Effects of mannose on Acanthamoeba castellanii proliferation and cytolytic ability to corneal epithelial cells. Invest Ophthalmol Vis Sci. 2003;44:3424-31.
• Suchecki JK, Donshik P, Ehlers WH. Contact lens complications. Ophthalmol Clin North Am. 2003;16:471-84.
• McCulley JP, Alizadeh H, Niederkorn JY. The diagnosis and management of Acanthamoeba keratitis. CLAO J. 2000 Jan;26(1):47-51.
• Walochnik J, Haller-Schober E, Kolli H, Picher D, Obwaller A, Aspock HJ. Discrimination between clinically relevant and nonrelevant Acanthamoeba strains isolated from contact lens-wearing keratitis patients in Austria. Clin. Microbiol. 2000;38:3932-6.
• Jaison PL, Cao Z, Panjwani N. Binding of Acanthamoeba to [corrected] mannose-glycoproteins of corneal epithelium: effect of injury. Curr Eye Res 1998;17:770-6. Erratum in: Curr Eye Res. 1998;17(10):1036.
• Leher HF, Alizadeh H, Taylor WM, Shea AS, Silvany RS, Van Klink F, et al. Role of mucosal IgA in the resistance to Acanthamoeba keratitis. Invest Ophthalmol Vis Sci. 1998;39:2666-73.
• Leher H, Silvany R, Alizadeh H, Huang J, Niederkorn JY. Mannose induces the release of cytopathic factors from Acanthamoeba castellanii. Infect Immun. 1998;66:5-10.
• Schaumberg DA, Snow KK, Dana MR. The epidemic of Acanthamoeba keratitis: where do we stand? Cornea. 1998;17:3-10.
• Stothard DR, Schroeder-Diedrich JM, Awwad MH, Gast RJ, Ledee DR, Rodriguez-Zaragoza S, et al. The evolutionary history of the genus Acanthamoeba and the identification of eight new 18S rRNA gene sequence types. J. Eukaryot Microbiol. 1998;45:45-54.
• Martinez AJ, Visvesvara GS. Free-living, amphizoic and opportunistic amebas. Brain Pathol. 1997;7:583-598.
• Yang Z, Cao Z, Panjwani N. Pathogenesis of Acanthamoeba keratitis: carbohydrate-mediated host-parasite interactions. Infect Immun. 1997;65:439-45.
• Ledee DR, Hay J, Byers TJ, Seal DV, Kirkness CM. Acanthamoeba griffini. Molecular characterization of a new corneal pathogen. Invest Ophthalmol Vis. Sci 1996;37:544-50.
• Chynn EW, Lopez MA, Pavan-Langston D, Talamo JH. Acanthamoeba keratitis. Contact lens and noncontact lens characteristics. Ophthalmology. 1995 Sep;102(9):1369-73.
• Winchester K, Mathers WD, Sutphin JE, Daley TE. Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy. Cornea. 1995 Jan;14(1):10-7.
• Morton LD, McLaughlin GL, Whiteley HE. Effects of temperature, amebic strain, and carbohydrates on Acanthamoeba adherence to corneal epithelium in vitro. Infect Immun. 1991;59:3819-22.
• Ma P, Visvesvara GS, Martinez AJ, Theodore FH, Daggett PM, Sawyer TK. Naegleria and Acanthamoeba infections: Review. Rev Infect Dis. 1990; 12:490-513.
• Visvesvara GS, Stehr-Green JK. Epidemiology of free-living ameba infections. J Protozool. 1990;37:25S-33S.
• Brandt FH, Ware DA, Visvesvara GS. Viability of Acanthamoeba cysts in ophthalmic solutions. Appl Environ Microbiol. 1989;55:1144-6.
• Simitzis-Le Flohic AM, Hasle DP, Paniagua-Crespo E, Colin J, Lagoutte F, Donval A, et al. Acanthamoeba keratitis. Epidemiologic and parasitologic study. J Fr Ophtalmol. 1989;12:361-6.
• Stehr-Green JK, Bailey TM, Visvesvara GS. The epidemiology of Acanthamoeba keratitis in the United States. Am J Ophthalmol. 1989;107:331-6.
• Biddick CJ, Rogers LH, Brown TJ. Viability of pathogenic and nonpathogenic free-living amoebae in long-term storage at a range of temperatures. Appl Environ Microbiol. 1984;48:859-60.
• Pussard, M. , and Pons, R. Morphologie de la paroi kystique et taxonomie du genre Acanthamoeba (Protozoa, Amoebida). Protistologica. 1977;13:557-98.
• Neff RJ, Neff RH. The biochemistry of amoebic encystment. Symp Soc Exp Biol. 1969;23:51-81.