CAS No. 302-01-2 Hydrazine; CAS No. 57-14-7 1 Dimethylhydrazine; CAS No. 540-73-8 1,2-Dimethylhydrazine
Hydrazines (H₂NNH₂) are clear, colorless liquids with an ammonia-like odor. Hydrazines are highly reactive and easily catch fire. Workers may be harmed from exposure to hydrazine. The level of harm depends upon the dose, duration, and work being done.
Hydrazine is used in many industries, such as the manufacturing of rocket propellants and fuels for spacecraft. Some examples of workers at risk of being exposed to hydrazine include the following:
- Worker who use it for boiler water treatments to protect against corrosion
- Workers in industries where it is used as a chemical reactant
- Workers who participate in cancer research
- Agricultural workers who use it in pesticides
NIOSH recommends that employers use Hierarchy of Controls to prevent injuries. If you work in an industry that uses hydrazine, please read chemical labels and the accompanying Safety Data Sheets for hazard information. Visit NIOSH’s page on Managing Chemical Safety in the Workplace to learn more about controlling chemical workplace exposures.
The following resources provide information about occupational exposure to hydrazine. Useful search terms for hydrazine include “diamine,” “hydrazine (anhydrous),” and “hydrazine base.”
The NIOSH Pocket Guide to Chemical Hazards (NPG) helps workers, employers, and occupational health professionals recognize and control workplace chemical hazards.
The NIOSH Manual of Analytical Methods (NMAM) is a collection of methods for sampling and analysis of contaminants in workplace air, and in the blood and urine of workers who are occupationally exposed.
The Health Hazard Evaluation Program (HHE) conducts onsite investigations of possible worker exposure to chemicals. Search the HHE database for more information on hydrazine.
- NIOSHTIC-2 search results for hydrazines—NIOSHTIC-2 is a searchable database of worker safety and health publications, documents, grant reports, and journal articles supported in whole or in part by NIOSH.
- NIOSH Worker Health Study Summaries—NIOSH conducts research to prevent illnesses and injuries in the workplace.
- NIOSH skin notation (SK) profile: Hydrazine—Understanding the hazards related to skin contact with chemicals is a critical component of modern occupational safety and health programs.
- Immediately Dangerous to Life or Health (IDLH) Value Profile: Hydrazine—NIOSH reviews relevant scientific data and researches methods for developing IDLH values.
- Criteria for a Recommended Standard: Occupational Exposure to Hydrazine DHHS (NIOSH) Publication No. 78-172 (1978)– Presents a standard to prevent the adverse effects of exposure to hydrazine over a working lifetime.
- Occupational Safety and Health Guideline for Hydrazine—This guideline helps stakeholders conduct effective occupational safety and health programs.
- ATSDR ToxFAQs for Hydrazine
- ATSDR Toxicological Profile for Hydrazines
- EPA Acute Exposure Guideline Levels: Hydrazine
- EPA Air Toxics: Hydrazine
- EPA Integrated Risk Information System: Hydrazine
- NLM Hazardous Substance Data Bank: Hydrazine
- NLM Haz-Map: Hydrazine
- National Cancer Institute Cancer Topics: Hydrazine Sulfate
- NTP Carcinogen Reports 14th Edition 2016: Hydrazine, Hydrazine Sulfate
- OSHA Safety and Health Topics: Hydrazine
- New Jersey Hazardous Substance Fact Sheets: Hydrazine
- EPA Chemistry Dashboard
- OSHA Hazard Communication
- IARC Monographs Vol 115 (2018): Hydrazine
- IARC Monographs Vol. 71: Hydrazine
- European Chemicals Agency (ECHA): Search for hydrazines
- Gestis Substance Database
- ILO International Safety Cards for Hydrazines
Table 0147 1,1-DIMETHYLHYDRAZINE – (Dimethylhydrazine, N,N-Dimethylhydrazine, unsym-Dimethylhydrazine, UDMH) 0180 METHYL HYDRAZINE – (Monomethylhydrazine, MMH) 0263 1,2-DIPHENYLHYDRAZINE – (Hydrazobenzene, Diphenylhydrazine, N,N’-Bianiline) 0281 HYDRAZINE – (Diamide, Diamine, Nitrogen hydride, (anhydrous)) 0938 PHENYLHYDRAZINE – (Hydrazinobenzene, Monophenylhydrazine) 1662 1,2-DIMETHYLHYDRAZINE – (Symmetrical dimethylhydrazine, N,N’-Dimethylhydrazine, SDMH)
- IPCS INCHEM: Hydrazine
- OECD Global Portal to Information on Chemical Substances
- WHO (Environmental Health Criteria 68): Hydrazine
- WHO (Health and Safety Guide No. 56): Hydrazine
- Japan (Chemicals Evaluation and Research Institute): Hydrazine
- Page last reviewed: November 2, 2018
- Page last updated: November 2, 2018
- Content source:
- National Institute for Occupational Safety and Health Education and Information Division