Immediately Dangerous to Life or Health Concentrations (IDLH)
CAS number: 78–93–3
NIOSH REL: 200 ppm (590 mg/m3) TWA, 300 ppm (885 mg/m3) STEL
Current OSHA PEL: 200 ppm (590 mg/m3) TWA
1989 OSHA PEL: 200 ppm (590 mg/m3) TWA, 300 ppm (885 mg/m3) STEL
1993-1994 ACGIH TLV: 200 ppm (590 mg/m3) TWA, 300 ppm (885 mg/m3) STEL
Description of Substance: Colorless liquid with a moderately sharp, fragrant, mint- or acetone-like odor.
LEL(@200EF): 1.4% (10% LEL(@200EF), 1,400 ppm)
Original (SCP) IDLH: 3,000 ppm
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Patty  that a 2-hour exposure of rats to 2,000 ppm caused no deaths, but 4 of 6 rats exposed to 4,000 ppm for a 2-hour period died [Smyth 1956].
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA
Lethal concentration data:
Lethal dose data:
|RatMouse||Kimura et al. 1971Tanii et al. 1986||oraloral||2,7374,050||———-||6,386 ppm9,450 ppm||639 ppm945 ppm|
Human data: It has been reported that 3,000 ppm is irritating to the eyes and nose [Patty et al. 1935].
|Revised IDLH: 3,000 ppm [Unchanged]Basis for revised IDLH: Based on acute inhalation toxicity data in humans [Patty et al. 1935], the original IDLH for 2-butanone (3,000 ppm) is not being revised at this time.|
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