Ethylamine

May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

CAS number: 75–04–7

NIOSH REL: 10 ppm (18 mg/m3) TWA

Current OSHA PEL: 10 ppm (18 mg/m3) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 5 ppm (9.2 mg/m3) TWA, 15 ppm (27.6 mg/m3) STEL

Description of Substance: Colorless gas or water-white liquid (below 62 F) with an ammonia-like odor.

LEL:. . 3.5% (10% LEL, 3,500 ppm)

Original (SCP) IDLH: 4,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1958] report that a 4-hour exposure to 4,000 ppm killed 1 of 6 rats.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA

Lethal concentration data:

Species Reference LC50(ppm) LCLo(ppm) Time Adjusted 0.5-hrLC (CF) Derivedvalue
RatMammal

Rat

Hine et al. 1960Kulagina 1975

UCC 1958

—–1,230

—–

3,000—–

4,000

4 hr?

4 hr

6,000 ppm (2.0)?

8,000 ppm (2.0)

600 ppm?

800 ppm

 

Lethal dose data:

Species Reference Route LD50(mg/kg) LDLo(mg/kg) Adjusted LD Derived value
Rat UCC 1958 oral 400 —– 1,497 ppm 150 ppm

 

Human data: None relevant for use in determining the revised IDLH.

 

REFERENCES:

1. Hine CH, Kodama JK, Guzman RJ, Loquvam GS [1960]. The toxicity of allylamines. Arch Environ Health 1:343-352.

2. Kulagina NK [1975]. Dependence of biological activity of aliphatic hydrocarbons on their chemical structure and physical-chemical properties. Toksikol Nov Prom Khim Vesh 14:80-90 (in Russian).

3. Smyth HF Jr, Carpenter CP, Weil CS, Pozzani UC [1954]. Range-finding toxicity data: list V. AMA Arch Ind Hyg Occup Med 10:61-68.

4. UCC [1958]. Toxicology studies: ethyl amine. New York, NY: Union Carbide Corporation.

Page last reviewed: December 4, 2014