Immediately Dangerous to Life or Health Concentrations (IDLH)
CAS number: 107–06–2
NIOSH REL: 1 ppm (4 mg/m3) TWA, 2 ppm (8 mg/m3) STEL; NIOSH considers ethylene dichloride to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990].
Current OSHA PEL: 50 ppm TWA, 100 ppm CEILING,
200 ppm 5-minute MAXIMUM PEAK in any 3 hours
1989 OSHA PEL: 1 ppm (4 mg/m3) TWA, 2 ppm (8 mg/m3) STEL
1993-1994 ACGIH TLV: 10 ppm (40 mg/m3) TWA
Description of Substance: Colorless liquid with a pleasant, chloroform-like odor.
LEL:. . 6.2% (10% LEL, 6,200 ppm)
Original (SCP) IDLH: 1,000 ppm
Basis for original (SCP) IDLH: The chosen IDLH is based on the maximum time-concentration in air of 1,000 ppm which was survived by female rats for 1.5 hours [Spencer et al. 1951 cited by Patty 1963]. The chosen IDLH is further supported by the rat 4-hour LCLO of 1,000 ppm [Carpenter et al. 1949 cited by NIOSH 1976].
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA
Lethal concentration data:
|Species||Reference||LC50(ppm)||LCLo(ppm)||Time||Adjusted 0.5-hrLC (CF)||Derivedvalue|
|Arch Exp Pathol Pharmacol 1929Carpenter et al. 1949
Heppel et al. 1945
Heppel et al. 1945
Spencer et al. 1951
|2 hr4 hr
|1,947 ppm (1.6)2,000 ppm (2.0)
7,200 ppm (2.4)
3,600 ppm (2.4)
7,200 ppm (2.4)
2,400 ppm (2.4)
|195 ppm200 ppm
Other animal data: It has been reported that female rats survived a 1.5-hour exposure to 1,000 ppm [Spencer et al. 1951].
Human data: In one study, 1 of 6 workers reported symptoms such as nausea, vomiting, and dizziness from exposures between 10 and 37 ppm [Brzozowski et al. 1954].
|Revised IDLH: 50 ppmBasis for revised IDLH: The revised IDLH for ethylene dichloride is 50 ppm based on acute inhalation toxicity data in workers [Brzozowski et al. 1954]. [Note: NIOSH recommends as part of its carcinogen policy that the “most protective” respirators be worn for ethylene dichloride at concentrations above 1 ppm.]|
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