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Registry of Toxic Effects of Chemical Substances (RTECS)

Sulfur dioxide

RTECS #

WS4550000

CAS #

7446-09-5; 8014-94-6; 12396-99-5; 83008-56-4; 89125-89-3

Updated

June 2017

Molecular Weight

64.06

Molecular Formula

O2S

Synonyms

Fermenicide liquid
Fermenicide powder
Schwefeldioxyd (German)
Siarki dwutlenek (Polish)
Sulfur dioxide (ACGIH:OSHA)
Sulfur oxide
Sulfur superoxide
Sulfurous acid anhydride
Sulfurous anhydride
Sulfurous oxide
Sulphur dioxide

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 6 ppm/32D mildJPCAAC 10,17,1960

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysismultiple/human42 mg/m3MUREAV 359,25,1996
Cytogenetic Analysisother cell types/domestic animal5 mmol/LMUREAV 39,149,1977
Cytogenetic Analysisother cell types/cattle2500 µmol/LMUREAV 39,149,1977
Cytogenetic Analysisinhalation/mouse14 µg/L/4H/7DMUTAEX 17,215,2002
DNA adductinhalation/rat72 mg/kg/300D- intermittentCALEDQ 139,189,1999
DNA Damageinhalation/mouse7 µg/LTXAPA9 197,239,2004
DNA Damageinhalation/mouse14 µg/L/7D- intermittentEMMUEG 46,150,2005
DNA Damagelymphocyte/human5700 ppbMUREAV 39,149,1977
DNA inhibitionlymphocyte/human5700 ppbMUREAV 39,149,1977
micronucleus testinhalation/mouse28 µg/L/5D- intermittentINHTE5 15,1053,2003
mutation in microorganisms/Other microorganisms10 mmol/L (-enzymatic activation step)MUREAV 39,149,1977
mutation in microorganisms/Saccharomyes cerevisiae5 µmol/L (-enzymatic activation step)MUREAV 39,149,1977
other mutation test systems/Escherichia coli2 mmol/LCBINA8 43,289,1983
other mutation test systemslymphocyte/human5700 ppbMUREAV 39,149,1977
other mutation test systemsother cell types/cattle2500 µmol/LMUREAV 39,149,1977
sex chromosome loss and nondisjunctionoral/Drosophila melanogaster200 µmol/LMUREAV 39,149,1977
sister chromatid exchangemultiple/human42 mg/m3MUREAV 359,25,1996
sperm morphologyinhalation/mouse10 ppm/3H/8W- intermittentFCTOD7 94,103,2016

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
inhalation/rat 4 mg/m3/24H (72D prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Maternal effects: Parturition

Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)
HYSAAV 35(4-6),277,1970
inhalation/rat 4 mg/m3/24H (72D prior to copulation)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Delayed effects
HYSAAV 35(4-6),277,1970
inhalation/rat 4970 µg/m3/12H (12W prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
HYSAAV 36(7-9),178,1971
inhalation/rat 30 ppm/6H (21W male)Reproductive: Paternal effects: Testes, epididymis, sperm ductJTEHD6 21,141,1987
inhalation/mouse 25 ppm/7H (6-15D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)FCTXAV 18,743,1980
inhalation/mouse 25 ppm/7H (6-15D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemNTIS** CONF-771017
inhalation/mouse 32 ppm/24H (7-18D pregnant)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Behavioral
TJADAB 31,9B,1985
inhalation/mouse 5 ppm (9D prior to copulation/1-14D pregnant)Reproductive: Effects on newborn: BehavioralNETEEC 20,543,1998
inhalation/rabbit 70 ppm/7H (6-18D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemNTIS** CONF-771017

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 500 ppm/5M/30W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors
BJCAAI 21,606,1967
inhalation/rat lowest published toxic concentration: 72 mg/kg/300D- intermittentTumorigenic: Carcinogenic by RTECS criteria

Tumorigenic: Facilitates action of known carcinogens

Lung, Thorax, or Respiration: Tumors
CALEDQ 139,189,1999

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/frog Lowest published lethal concentration: 1 pph/15MHBAMAK 4,1396,1935
inhalation/guinea pig lowest published toxic concentration: 100 ppm/30MCardiac: Pulse rate decreased with fall in BPTOXID9 66,193,2002
inhalation/guinea pig lowest published toxic concentration: 100 ppm/1HTOXID9 60,425,2001
inhalation/guinea pig lowest published toxic concentration: 50 ppm/1HOlfaction: Other olfaction effects

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Other changes
TOXID9 60,425,2001
inhalation/guinea pig Lowest published lethal concentration: 1039 ppm/24HCBTIAE 10,281,1939
inhalation/human lowest published toxic concentration: 2.2 mg/m3/30MLung, Thorax, or Respiration: Other changesVCVN5* -,226,1993
inhalation/human lowest published toxic concentration: 2.9 mg/m3/60MOlfaction: Other olfaction effectsVCVN5* -,226,1993
inhalation/human lowest published toxic concentration: 2.9 mg/m3/10MCardiac: Pulse rate increased without fall in BP

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,226,1993
inhalation/human Lowest published lethal concentration: 1000 ppm/10MLung, Thorax, or Respiration: Respiratory depressionCTOXAO 5,198,1972
inhalation/human lowest published toxic concentration: 3 ppm/5DLung, Thorax, or Respiration: Other changesTXAPA9 22,319,1972
inhalation/human lowest published toxic concentration: 12 ppm/1HLung, Thorax, or Respiration: Other changesSAIGBL 14,449,1972
inhalation/human Lowest published lethal concentration: 3000 ppm/5MTABIA2 3,231,1933
inhalation/mammal (species unspecified) lowest published toxic concentration: 19.6 mg/m3Brain and Coverings: Other degenerative changes

Lung, Thorax, or Respiration: Other changes

Endocrine: Other changes
VCVN5* -,224,1993
inhalation/mammal (species unspecified) lowest published toxic concentration: 80 mg/m3Olfaction: Change in sensation of smell

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,224,1993
inhalation/mammal (species unspecified) lowest published toxic concentration: 740 mg/m3Olfaction: Other olfaction effects

Gastrointestinal: Decreased motility or constipation
VCVN5* -,224,1993
inhalation/mammal (species unspecified) Lowest published lethal concentration: 3000 ppm/5MAEPPAE 138,65,1928
inhalation/mouse lethal concentration (50 percent kill): 3000 ppm/30MBehavioral: Convulsions or effect on seizure threshold

Behavioral: Change in motor activity (specific assay)
JCTODH 4,236,1977
inhalation/mouse lethal concentration (50 percent kill): 3000 ppm/30MENTOX* ,115,2005
inhalation/rat lowest published toxic concentration: 20 mg/m3/5HBehavioral: Change in motor activity (specific assay)

Behavioral: Aggression
VCVN5* -,225,1993
inhalation/rat lowest published toxic concentration: 30 mg/m3Peripheral Nerve and Sensation: Recording from peripheral motor nerve

Blood: Normocytic anemia

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)
VCVN5* -,225,1993
inhalation/rat lethal concentration (50 percent kill): 2168 mg/m3Behavioral: Change in motor activity (specific assay)

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,224,1993
inhalation/rat lowest published toxic dose: 57.3 mg/m3/6HVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lowest published toxic concentration: 80 mg/m3/4HLung, Thorax, or Respiration: Other changesTPKVAL 14,73,1975
inhalation/rat lowest published toxic concentration: 57.3 mg/m3/6HVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lethal concentration (50 percent kill): 2520 ppm/1HENTOX* ,115,2005

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/cattle lowest published toxic concentration: 1 ppm/10D- intermittentLung, Thorax, or Respiration: Other changes

Blood: Other changes

Immunological Including Allergic: Decrease in cellular immune response
TOXID9 72,230,2003
inhalation/cattle lowest published toxic concentration: 5 ppm/7D- intermittentLung, Thorax, or Respiration: Other changes

Blood: Other changes

Immunological Including Allergic: Decrease in cellular immune response
TOXID9 72,230,2003
inhalation/Dog lowest published toxic concentration: 1 ppm/90M/1Y- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchiAEHLAU 30,249,1975
inhalation/Dog lowest published toxic concentration: 500 ppm/2H/21W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory depression
JTEHD6 13,945,1984
inhalation/guinea pig lowest published toxic concentration: 10 ppm/1H/30D- intermittentLiver: Other changes

Kidney, Ureter, and Bladder: Other changes

Biochemical: Metabolism (intermediary): Lipids including transport
INHEAO 23,81,1985
inhalation/human lowest published toxic concentration: 4.5 mg/m3/24H/5D- continuousRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN5* -,227,1989
inhalation/mouse lowest published toxic concentration: 22 mg/m3/6H/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductasesETOPFR 13,1,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/6H/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: CatalasesETOPFR 13,1,2003
inhalation/mouse lowest published toxic concentration: 14 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Immunological Including Allergic: Increase in cellular immune response
INHTE5 17,303,2005
inhalation/mouse lowest published toxic concentration: 28 mg/m3/5D- intermittentLung, Thorax, or Respiration: Changes in lung weight

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight
INHTE5 15,1053,2003
inhalation/mouse lowest published toxic concentration: 64 mg/m3/7D- intermittentBrain and Coverings: Other degenerative changes

Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
AECTCV 45,423,2003
inhalation/mouse lowest published toxic concentration: 22 mg/m3/7D- intermittentGastrointestinal: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
INHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
INHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductasesINHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 112 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: CatalasesINHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 10 ppm/7W- intermittentBehavioral: Food intake (animal)

Behavioral: Alteration of operant conditioning

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
NETEEC 29,211,2007
inhalation/mouse lowest published toxic dose: 10 ppm/7D- intermittentBlood: Other changesMUREAV 697,38,2010
inhalation/mouse lowest published toxic concentration: 10 ppm/3H/8W- intermittentReproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct

Behavioral: Fluid intake
FCTOD7 94,103,2016
inhalation/rabbit lowest published toxic concentration: 200 mg/m3/3H/13W- intermittentCardiac: Other changes

Liver: Other changes

Blood: Hemorrhage
GISAAA 24(6),22,1959
inhalation/rat lowest published toxic concentration: 28.6 mg/m3/3D- intermittentVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLiver: Other changes

Biochemical: Metabolism (intermediary): Other proteins
TXCYAC 216,253,2005
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
TOLED5 160,34,2005
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
TOLED5 160,34,2005
inhalation/rat lowest published toxic concentration: 7 mg/m3/4H/30D- intermittentBrain and Coverings: Other degenerative changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Metabolism (intermediary): Effect on mitochondrial function
TXCYAC 300,67,2012
inhalation/rat lowest published toxic concentration: 5.6 mg/m3/4H/4W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOLED5 214,320,2012
inhalation/rat lowest published toxic concentration: 300 ppm/4H/44D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other hydrolases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
EJPHAZ 487,7,2004
inhalation/rat lowest published toxic concentration: 300 ppm/2H/10D- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory depression
TXAPA9 197,175,2004
inhalation/rat lowest published toxic concentration: 10 ppm/1H/6W- intermittentBrain and Coverings: Other degenerative changes

Eye: Other eye effects

Behavioral: Food intake (animal)
NETEEC 25,587,2003
inhalation/rat lowest published toxic concentration: 10 ppm/1H/6W- intermittentBehavioral: Fluid intake

Biochemical: Metabolism (intermediary): Lipids including transport
NETEEC 25,587,2003
inhalation/rat lowest published toxic concentration: 8.5 mg/m3/24H/65D- continuousPeripheral Nerve and Sensation: Recording from peripheral motor nerve

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Emphysema
VCVN5* -,228,1989
inhalation/rat lowest published toxic concentration: 143 mg/m3/6H/17W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Hepatitis (hepatocellular necrosis), diffuse

Endocrine: Hyperglycemia
VCVN5* -,229,1989
inhalation/rat lowest published toxic concentration: 51.2 mg/m3/6H/17W- intermittentOlfaction: Other olfaction effects

Gastrointestinal: Other changes

Liver: Liver function tests impaired
VCVN5* -,229,1989
inhalation/rat lowest published toxic concentration: 100 ppm/5H/28D- intermittentLung, Thorax, or Respiration: Other changes

Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
CBPCEE 114,89,1996
inhalation/rat lowest published toxic concentration: 4910 µg/m3/6H/17W- intermittentBlood: Pigmented or nucleated red blood cells

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
GISAAA 41(5),6,1976
inhalation/rat lowest published toxic concentration: 500 µg/m3/96D- intermittentBrain and Coverings: Changes in surface EEG

Behavioral: Change in motor activity (specific assay)

Biochemical: Metabolism (intermediary): Xanthine, purine or nucleotides including urate
GISAAA 34(2),3,1969
inhalation/rat lowest published toxic concentration: 400 ppm/3H/6W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchiATSUDG 9,431,1986
inhalation/rat lowest published toxic concentration: 10 ppm/24H/14D- intermittentBehavioral: Food intake (animal)

Liver: Other changes

Biochemical: Metabolism (intermediary): Lipids including transport
ARTODN 70,164,1996
parenteral/rat lowest published toxic dose: 250 ppm/4D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other
TOXID9 44,190,2005

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-short term exposure limit 0.25 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 54,131,1992
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 54,131,1992
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 54,131,1992
TOXICOLOGY REVIEWEVHPAZ 11,163,1975
TOXICOLOGY REVIEWNTIS** PB228-002
TOXICOLOGY REVIEWEVHPAZ 10,35,1975
TOXICOLOGY REVIEWGEIGAI 20,299,1973
TOXICOLOGY REVIEWAEHLAU 16,903,1968
TOXICOLOGY REVIEWENVRAL 16,139,1978
TOXICOLOGY REVIEWNTIS** CONF-691001
TOXICOLOGY REVIEWAMIHBC 10,455,1954
TOXICOLOGY REVIEWMUREAV 558,7,2004
TOXICOLOGY REVIEWTOLED5 140-141,195,2003
TOXICOLOGY REVIEWTOLED5 140-141,213,2003
TOXICOLOGY REVIEWTPHSDY 23,311,2002
TOXICOLOGY REVIEWTPHSDY 24,609,2003
TOXICOLOGY REVIEWNETOX* 26,555,2005
TOXICOLOGY REVIEWDIMON* 46,551,2000
TOXICOLOGY REVIEWENTOX* -,115,2005
TOXICOLOGY REVIEWMUREAV 658,124,2008
TOXICOLOGY REVIEWHUTOX* -,259,1996
TOXICOLOGY REVIEWHUTOX* -,661,1996
TOXICOLOGY REVIEWMUREAV 674,45,2009
TOXICOLOGY REVIEWMUREAV 674,62,2009
TOXICOLOGY REVIEWMUREAV 674,73,2009
TOXICOLOGY REVIEWMUREAV 636,144,2007
TOXICOLOGY REVIEWMUREAV 636,36,2007
TOXICOLOGY REVIEWPRESR* 7,123,2006
TOXICOLOGY REVIEWMUREAV 717,38,2011
TOXICOLOGY REVIEWMUREAV 717,46,2011
TOXICOLOGY REVIEWMUREAV 762,76,2014
TOXICOLOGY REVIEWMUREAV 765,19,2015
TOXICOLOGY REVIEWMUREAV 768,27,2016
TOXICOLOGY REVIEWTXCYAC 325,74,2014

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,320,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 5 ppm (13 mg/m3)DTLVS* 3,238,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 ppm (5.2 mg/m3), short term exposure limit 5 ppm (13 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 2 ppm (5 mg/m3);KZW 4 ppm (10 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 2 ppm (5.3 mg/m3), short term exposure limit 5 ppm (13 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 ppm (1.3 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 1 ppm (2.7 mg/m3), short term exposure limit 4 ppm (11 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 2 ppm (5 mg/m3), VLE 5 ppm (10 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 0.5 ppm (1.3 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 5 mg/m3, short term exposure limit 5 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 ppm (1.3 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 2 ppm (5 mg/m3), short term exposure limit 5 ppm (10 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2 ppm (5 mg/m3);short term exposure limit 5 ppm (10 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 ppm (5.2 mg/m3), short term exposure limit 5 ppm (13 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 2 ppm (5,2 mg/m3); short term exposure limit 5 ppm (13 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 2 mg/m3, MAC(short term exposure limit) 5 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 10 mg/m3, Skin, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 2 ppm (5 mg/m3), ceiling concentration 5 ppm (13 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 0.5 ppm (1.3 mg/m3), JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 5 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SULFUR DIOXIDE-air10H time-weighted average 2 ppm;short term exposure limit 5 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 70860; Number of Industries 59; Total Number of Facilities 2465; Number of Occupations 58; Total Number of Employees Exposed 55033; Total Number of Female Employees Exposed 8990
National Occupational Hazard Survey 1974Hazard Code 70860; Number of Industries 85; Total Number of Facilities 6399; Number of Occupations 61; Total Number of Employees Exposed 51398

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/122020)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Sulfur dioxide, 6004
OSHA ANALYTICAL METHOD #ID-104 (for impinger)
OSHA ANALYTICAL METHOD #ID200
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