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Hepatitis B - Vaccination of Adults


Hepatitis B virus (HBV) is transmitted via blood or sexual contact. People with chronic HBV infection are at increased risk for cirrhosis and liver cancer and require medical care. ACIP recommends vaccination of adults at risk for HBV infection, including universal vaccination of adults in settings in which a high proportion have risk factors for HBV infection and vaccination of adults requesting protection from HBV without acknowledgment of a specific risk factor.

Guidelines and Recommendations

Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices
MMWR Recommendations and Reports / January 12, 2018 / 67(1);1–31

Hepatitis B Vaccination, Screening, and Linkage to Care: Best Practice Advice From the American College of Physicians and CDC

Implementation Guidelines

To ensure vaccination of persons at risk for HBV infection, health care providers should

Immunization Schedules and Dosages

Adult Immunization Schedule

Recommended doses of Hepatitis B vaccines (by age group and vaccine type)

Standing Orders

Use of Standing Orders Programs to Increase Adult Vaccination Rates: Recommendations of the Advisory Committee on Immunization Practices
MMWR 2000;49(RR-1):15–26

Standing Orders for Administering Hepatitis B Vaccine to Adults [PDF – 1 page]

Vaccine Funding, Billing, and Reimbursement

Coding Guidelines for Vaccine Preventable Hepatitis [PDF – 2 pages]
Brochure from the American Medical Association that provides CPT and ICD coding guidelines for Hepatitis A and Hepatitis B in high-risk populations

Merck Vaccine Patient Assistance Program
Provides vaccines free of charge to eligible adults, primarily the uninsured

Specific Sites and Tools

Adults Only Vaccination: A Step-by-Step Guide (2004)
Guide from the Immunization Action Coalition to help integrate immunization services into health care settings new to vaccination

Related Pages


Travelers’ Health

Vaccines and Immunizations