06/24/2022: Lab Advisory: Culture-Based Testing Guidance for Monkeypox Virus
Audience: Clinical Laboratory Professionals
Level: Laboratory Advisory
Laboratory personnel should only perform culture-based testing for monkeypox virus if they have validated and appropriately approved protocols, BSL-3 containment facilities, and smallpox vaccinated staff as outlined on the Laboratory Procedures for Monkeypox Virus page.
CDC recommends that smallpox vaccinated laboratory staff who perform culture-based testing of lesion specimen material from a suspect monkeypox case for diagnostic purposes other than monkeypox virus (e.g., HSV or VSV) use BSL-2 facilities with BSL-3 practices. CDC recommends that unvaccinated staff use BSL-3 containment when performing these procedures.
- Monkeypox Information for Laboratory Personnel
- U.S. Monkeypox 2022: Situation Summary
- Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA
- Detection of monkeypox virus with real-time PCR assays
- If you are a clinical or public health laboratory professional, contact LOCS.
- For media inquiries, contact the CDC Newsroom.
- For all other questions, contact CDC-INFO.