National Inventory for Poliovirus Containment:

Minimizing Risk of Poliovirus Release from Laboratories in the United States

The US Poliovirus National Authority for Containment of Poliovirus (NAC), located in the Centers for Disease Control and Prevention, Center for Preparedness and Response, appreciates your participation in this survey. This survey is designed to collect relevant laboratory inventory data to ensure compliance with requirements established in the WHO Global Action Plan (GAPIII)external icon, as adapted for the WHO Region of the Americas. PerGAPIII, each country is required to complete a national inventory of poliovirus-containing materials. Unlike previous surveys, the 2018 survey focuses on institutions that may have poliovirus potentially infectious materials (PIM). PIM includes human respiratory secretion and fecal specimens collected for non-polio related work in a time and place where wild poliovirus (WPV) or vaccine-derived poliovirus (cVDPV) was circulating or where oral polio vaccine (OPV) was in use. Historical domestic and international specimens are more likely to fall into these categories. Additionally, PIM cultured in some common cell lines (see Appendix C: Common Cell Lines and Animals Susceptible to Poliovirus) in order to isolate other viruses of interest may have unintentionally amplified poliovirus, so respiratory or enteric viral isolates obtained from PIM specimens using any of these cell lines are also considered PIM.

The survey should be completed by laboratories, storage sites, or other facility types that test, extract, handle, or store biological samples from humans, experimentally infected animals, sewage, or environmental waters. The survey questions are intended to identify facilities that possess any materials that may contain poliovirus. The questions seek to distinguish between PIM containing wild poliovirus (WPV), circulating vaccine derived poliovirus (cVDPV), and oral poliovirus vaccine (OPV). With the release of the WHO PIM guidanceexternal icon in April 2018, extracted nucleic acid and specimens that may contain only OPV are no longer subject to containment under WHO GAP III. However, they are still considered to be part of the US inventory and should be reported.

For the purpose of this survey, PIM should be identified on the basis of where and when the specimens were collected, not on the basis of any test results see WHO’s Annex 2: Country or Territory-Specific Poliovirus Datapdf iconexternal icon. If your facility intends to destroy all of the potentially infectious poliovirus material or infectious material it possesses, you will then be asked to complete an attestation of destruction of the material. This attestation form will be sent to you once the completed survey is received.

Survey Overview

For an overview of the survey, please click herepdf icon. This document has been provided to help you prepare your survey responses and is not intended to be completed as a paper-based format. Appendices and other references can be found below. The survey must be completed online.

Survey Instructions

This survey is divided into six modules:

  1. Facility Information
  2. Material Types
  3. Inventory Information
  4. Disposition of Materials
  5. Key Facility Personnel
  6. Attestation

Throughout the survey, questions requiring a single answer are indicated by a circle (○) and check boxes (□) are used if multiple answers are permitted. Instructions are provided with certain questions. Definitions of key words used in the survey can be found in Appendix A. Please pay close attention to the instructions at the end of Modules A and B, as these will determine whether modules C and D need to be completed. Modules E and F will be completed by all survey recipients. The time needed to complete the online survey will vary depending on the complexity of your facility and the availability of needed information. If you begin the survey and then terminate it early, you will be provided with a return code via email. Click the survey link and enter the code when prompted by the system. Please contact poliocontainment@cdc.gov immediately if you have any questions about the survey or the questions it contains and someone will provide assistance.

National Inventory for Poliovirus Containment Survey

clipboard iconReady to take the National Inventory for Poliovirus Containment? Click here.

Notice!

If you have received an email directly from the NAC inviting you to participate in the National Inventory for Poliovirus Containment, please access the survey by clicking on the link provided at the bottom of the email.

If you no longer have the email, contact us at poliocontainment@cdc.gov and your survey link will be re-sent to you.

Appendices
Guidance for potentially infectious poliovirus materials (PIM)
National Inventory for Poliovirus Containment Survey

clipboard iconReady to take the National Inventory for Poliovirus Containment? Click here.

Notice!

If you have received an email directly from the NAC inviting you to participate in the National Inventory for Poliovirus Containment, please access the survey by clicking on the link provided at the bottom of the email.

If you no longer have the email, contact us at poliocontainment@cdc.gov and your survey link will be re-sent to you.

CDC has determined that the information collection activities conducted under the project are exempt from the requirements of the Paperwork Reduction Act (PRA) as they fall under the activities authorized under the National Childhood Vaccine  Injury Act (NCVIA) at section 2102(a)(6)-(a)(7) of the Public Health Service Act (42 USC 300aa-2(a)(6)-(a)(7).

Page last reviewed: September 23, 2020, 02:00 PM