Treatment and Screening

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Recommendations for Providing Quality STD Clinical Services (STD QCS)

CDC Recommendations for Providing Quality STD Clinical Services, 2020 (STD QCS) MMWR and a graphic explaining how STD QCS and the STI Treatment Guidelines can work together to optimize care.


STD Treatment Guidelines, 2015

2015 STD Treatment Guidelines

Recommendations for treating persons who have or are at risk for STDs. Includes regimens, evidence tables, wall chart, and pocket guide. The 2015 Guidelines are the most current version of this document. The 2015 Guidelines update the previous 2010 Guidelines with new diagnostic, treatment, and prevention recommendations for STDs.


Expedited Partner Therapy

Expedited Partner Therapy

Providing prescriptions or medications to the patient to take to his/her partner without the health care provider first examining the partner.


Additional STD Treatment Resources

Additional Resources

General STD treatment updates and resources, including Dear Colleague Letters, podcasts, and scientific articles.


The Diagnosis, Management and Prevention of Syphilis: An Update and Reviewpdf iconexternal icon – A clinical guidance document for use in the diagnosis and management of syphilis. Based on content from the 2015 CDC STD Treatment Guidelines, and developed by the NYC Department of Health and Mental Hygiene Bureau of Sexually Transmitted Infections and the NYC STD Prevention Training Center. (March 2019)

MMWR graphic

New CDC analysis suggests gay, bisexual, and other men who have sex with men (MSM) are at increased risk for extragenital STDs [i.e., chlamydia or gonorrhea in the throat or rectum] (April 11, 2019)

Syphilis Pocket Guide for Providerspdf icon – Updated booklet for providers containing need-to-know details on the diagnosis, treatment, and prevention of syphilis. (November 30, 2017)

National STD Curriculumexternal icon – An online modular learning experience that helps users learn how to manage STDs. It is continuously updated and integrates the most recent STD Treatment Guidelines. Free CME/CNE available. (November 1, 2017)

CDC Recommendations for Diagnosing and Managing Shigella Strains with Possible Reduced Susceptibility to Ciprofloxacin – This Health Advisory describes the identification of emerging Shigella strains with elevated minimum inhibitory concentration values for ciprofloxacin and outlines new recommendations for clinical diagnosis, management, and reporting, as well as new recommendations for laboratories and public health officials.

Emerging Drug-Resistant Gonorrhea: What’s New and What Now?external icon – Dr. Gail Bolan, Director of CDC’s Division of STD Prevention, discusses latest trends in drug resistant gonorrhea and provides an overview of treatment for this common sexually transmitted disease. (March 6, 2017)

Success Stories
Expedited Partner Therapy: Helping to Reduce Sexually Transmitted Infections
Illinois and Chicago working to expand the use of EPT to reach more partners with the medication they need.
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Two stories of PTCs in St. Louis and Denver whose innovative projects have gone above and beyond to meet the needs of providers.
Success Story
These training centers ensure clinicians have access to crucial clinical resources to help diagnose, treat, and prevent STDs.
Public Health and Primary Care: Forging Partnerships That Matter
California and New Hampshire programs working with primary care providers to improve the lives of people they serve.
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More STD Prevention Success Stories