Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Gonococcal Isolate Surveillance Project (GISP)

The Gonococcal Isolate Surveillance Project (GISP) was established in 1986 to monitor trends in antimicrobial susceptibilities of strains of N. gonorrhoeae in the United States in order to establish a rational basis for the selection of gonococcal therapies. GISP is a collaborative project among selected sexually transmitted diseases (STD) clinics, five regional laboratories, and the Centers for Disease Control and Prevention (CDC).

In GISP, N. gonorrhoeae isolates are collected from up to the first 25 men with urethral gonorrhea attending STD clinics each month in 26 cities in the United States. At regional laboratories, the susceptibilities of these isolates to penicillin, tetracycline, spectinomycin, ciprofloxacin, ceftriaxone, cefixime, and azithromycin are determined by agar dilution. Minimum inhibitory concentrations (MICs) are measured, and values are interpreted according to criteria recommended by the Clinical and Laboratory Standards Institute (CLSI).


Annual Reports and Profiles

Recent Publications

Sentinel Sites and Regional Laboratories

Click to download larger map
Click thumbnail for larger map

Sentinel Sites

  • Albuquerque, NM
  • Atlanta, GA
  • Birmingham, AL
  • Boston, MA
  • Buffalo, NY
  • Chicago, IL
  • Cleveland, OH
  • Columbus, OH
  • Dallas, TX
  • Greensboro, NC
  • Honolulu, HI
  • Indianapolis, IN
  • Kansas City, MO
  • Las Vegas, NV
  • Los Angeles, CA
  • Minneapolis, MN
  • New Orleans, LA
  • New York, NY
  • Orange County, CA
  • Philadelphia, PA
  • Phoenix, AZ
  • Pontiac, MI
  • Portland, OR
  • San Diego, CA
  • San Francisco, CA
  • Seattle, WA
  • Tripler Army Medical center, Honolulu, HI

Regional Labs

  • Emory University, Atlanta, GA
  • Johns Hopkins University, Baltimore, MD
  • Texas Department of State Health Services, Austin, TX
  • University of Alabama at Birmingham, AL
  • University of Washington, Seattle, WA

Forms & Coding Guide

Contact Us:
  • Centers for Disease Control and Prevention
    1600 Clifton Rd
    Atlanta, GA 30329-4027
  • 800-CDC-INFO
    TTY: (888) 232-6348
  • Contact CDC–INFO The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC-INFO