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Interim Recommendations for Persons with Possible Exposure to Avian Influenza During Outbreaks Among Poultry in the United States

This website is archived and is no longer being maintained or updated. For updated information on avian influenza, see the CDC Avian Influenza website and the World Health Organization (WHO) Avian Influenza Situation Update page.


Issued as Health Alert Network message on February 24, 2004.

Outbreaks of avian influenza A occur among U.S. poultry flocks from time to time. Since early February 2004, avian influenza outbreaks have been reported in several locations in the United States , most recently in Texas . This document briefly describes the current outbreak in Texas and provides interim guidance for persons who might be exposed to avian influenza; health-care professionals; and consumers of poultry.


The state of Texas has reported an outbreak of highly pathogenic avian influenza A (H5N2) among poultry on one farm in Gonzales County , in south-central Texas . This is the first outbreak of highly pathogenic avian influenza in the United States in 20 years and was detected by routine state monitoring for avian influenza.

Birds on this farm were sold to live bird markets in the Houston area. Preliminary testing of birds at two of these markets found evidence of avian influenza. The farm and the two live bird markets have been quarantined, cleaned, and disinfected following the culling of affected poultry. In addition, extensive surveillance measures have been instituted around the affected premises. CDC and the U.S. Department of Agriculture (USDA) are working with the Texas Department of Health and the Texas Animal Health Commission on both the human health and animal/veterinary aspects to contain this outbreak in poultry and minimize risk to humans. The health risk to humans from the H5N2 influenza outbreak in Texas is considered low at this time.

The H5N2 strain in Texas is a different subtype of influenza A than the virus affecting parts of Asia . The H5N1 outbreaks among poultry in Asia have been associated with human cases in Thailand and Vietnam . There is no epidemiologic link between the H5N1 virus in Asia and the H5N2 virus in Texas .

Avian influenza viruses typically do not infect humans; however, several instances of human infections and outbreaks of avian influenza have been reported since 1997 (for more information, see "Avian Influenza Infection in Humans"). It is believed that most cases of avian influenza infection in humans have resulted from contact with infected poultry or contaminated surfaces. Other means of transmission also are possible, such as the virus becoming aerosolized and landing on exposed surfaces of the mouth, nose, or eyes, or being inhaled into the lungs.

Interim CDC Recommendations

Because it is possible that avian influenza could be transmitted to humans, CDC is issuing the following interim U.S. guidance for 1) individuals who may be exposed to avian influenza, 2) health-care professionals, and 3) consumers of poultry. Guidance for individuals who may be exposed to avian influenza is based on the degree of risk associated with various levels and types of exposures. This document also contains interim guidance for health-care professionals who may need to evaluate, test, and diagnose potentially exposed individuals. Additionally, food safety information for consumers is provided to address concerns surrounding avian influenza outbreaks and poultry. The recommendations will be updated as necessary.

Individuals Participating in Avian Influenza Outbreak Control and Eradication Activities

Persons involved in outbreak control and eradication activities (e.g., euthanasia, carcass disposal, and cleaning and disinfection of premises affected by avian influenza) on poultry farms or live bird markets are at increased risk for exposure to avian influenza. Such persons often have prolonged, direct contact with infected birds and/or contaminated surfaces in an enclosed setting. CDC and USDA have developed interim guidance to reduce these risks, including recommendations about personal protective equipment, vaccination with seasonal influenza vaccine, administration of antiviral drugs for prophylaxis, surveillance and monitoring of workers, and evaluation of workers who develop a febrile respiratory illness within 7 days of their last exposure (available at

Other Individuals with Possible Exposure to Avian Influenza

The risks for exposure to avian influenza viruses and the possibility of viral reassortment would be expected to be lower for persons with more routine (i.e., less intense and prolonged) occupational or other types of contact with poultry or contaminated surfaces or equipment on affected farms or in live bird markets. Individuals who develop a febrile respiratory illness within a week after their last exposure to avian-infected or exposed birds or potentially contaminated surfaces should consult a health-care provider.   Before visiting a health-care setting, tell the provider about symptoms and recent possible exposures to avian influenza.

Health-Care Professionals: Evaluation of Ill Persons

Health-care providers should be alert for respiratory illness among persons who may have been exposed to infected poultry. The following section provides recommendations for health-care professionals who may need to evaluate symptomatic persons with possible avian influenza exposure.

Consumers: Food Safety Guidance

There is no evidence that any human cases of avian influenza have been acquired by eating poultry products. Influenza viruses such as H5N2, H7N2, and H5N1 are destroyed by adequate heat, as are other foodborne pathogens. Consumers are reminded to follow proper food preparation and handling practices, including:

More Information for People Who May be Exposed to Avian Influenza

"WHO interim recommendations for the protection of persons involved in the mass slaughter of animals potentially infected with highly pathogenic influenza viruses" and "Guidelines for the use of seasonal influenza vaccine in humans at risk of H5N1 infection" are available online.

The Occupational Safety & Health Administration's (OSHA) "Guidance for Protecting Workers Against Avian Flu" is available online.

For More Information

Page last modified February 24, 2004

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