Table 21. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by State, Ranked by Rates, United States, 2022

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Table 21. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by State, Ranked by Rates, United States, 2022
Rank* State Cases Rate per 100,000 Population
1 South Dakota 767 84.3
2 New Mexico 761 36.0
3 Arkansas 1,001 32.9
4 Oklahoma 1,278 31.8
5 Mississippi 913 31.1
6 Arizona 2,151 29.2
7 Montana 325 28.9
8 Nevada 902 28.4
9 Louisiana 1,225 26.7
10 Oregon 1,117 26.3
11 Washington 1,920 24.7
12 Missouri 1,454 23.5
13 Alabama 1,190 23.5
14 Delaware 238 23.4
15 North Carolina 2,473 23.1
16 Alaska 160 21.8
17 Florida 4,618 20.8
18 Ohio 2,402 20.4
19 California 7,849 20.1
20 Georgia 2,182 20.0
21 South Carolina 1,033 19.6
22 New York 3,603 18.3
US TOTAL† 59,016 17.7
23 Hawaii 231 16.0
24 Tennessee 1,126 16.0
25 Colorado 918 15.7
26 Texas 4,655 15.5
27 Kentucky 670 14.8
28 Maryland 781 12.7
29 Wisconsin 742 12.6
30 West Virginia 218 12.3
31 Rhode Island 133 12.2
32 Kansas 347 11.8
33 Minnesota 675 11.8
34 Massachusetts 824 11.8
35 Illinois 1,457 11.6
36 New Jersey 1,018 11.0
37 Nebraska 215 10.9
38 Virginia 936 10.8
39 Pennsylvania 1,397 10.8
40 Iowa 334 10.4
41 Indiana 686 10.0
42 Michigan 972 9.7
43 North Dakota 64 8.2
44 Utah 238 7.0
45 Connecticut 248 6.8
46 Idaho 118 6.1
47 Maine 82 5.9
48 New Hampshire 74 5.3
49 Wyoming 21 3.6
50 Vermont 3 0.5
* States were ranked by rate, then case count, then in alphabetical order, with rates shown rounded to the nearest tenth.
† Total includes cases reported by the District of Columbia with 271 cases and a rate of 40.3, but excludes territories.
NOTE: See Technical Notes for more information on syphilis case reporting. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information.

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