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Registry of Toxic Effects of Chemical Substances (RTECS)

n-Propyl nitrate

RTECS #

UK0350000

CAS #

627-13-4

Updated

September 2013

Molecular Weight

105.11

Molecular Formula

C3H7NO3

Synonyms

Nitrate de propyle normal (French)
Nitric acid, propyl ester
n-Propyl nitrate (ACGIH:OSHA)
Propyl nitrate
Propylester kyseliny dusicne (Czech)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lowest published lethal concentration: 5816 ppm/4HBehavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis
AIHAAP 19,80,1958
inhalation/rat Lowest published lethal concentration: 5816 ppm/4HBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Cyanosis
AIHAAP 19,80,1958
intravenous/cat lowest published lethal dose: 100 mg/kgJPETAB 118,77,1956
intravenous/Dog lowest published lethal dose: 200 mg/kgJPETAB 118,77,1956
intravenous/rabbit lethal dose (50 percent kill): 200 mg/kgJPETAB 118,77,1956

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 25 ppm;short term exposure limit 40 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 25 ppm (110 mg/m3)DTLVS* 3,217,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 25 ppm (107 mg/m3), short term exposure limit 40 ppm (172 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 25 ppm (110 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 25 ppm (109 mg/m3), short term exposure limit 40 ppm (174 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 25 ppm (110 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 25 ppm (110 mg/m3), short term exposure limit 40 ppm (170 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 25 ppm (105 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 25 ppm (110 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 25 ppm (105 mg/m3), short term exposure limit 40 ppm (170 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 25 ppm (105 mg/m3);short term exposure limit 40 ppm (170 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 25 ppm (107 mg/m3), short term exposure limit 40 ppm (172 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 20 ppm (90 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 25 ppm (107 mg/m3); short term exposure limit 40 ppm (172 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 25 ppm (110 mg/m3), KZG-week 50 ppm (220 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 1 10 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 25 ppm (110 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 25 ppm (110 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 25 ppm (110 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 25 ppm (110 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 25 ppm (110 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 25 ppm (110 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO n-PROPYL NITRATE-air10H time-weighted average 25 ppm;short term exposure limit 40 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code X7139; Number of Industries 2; Total Number of Facilities 30; Number of Occupations 2; Total Number of Employees Exposed 1844; Total Number of Female Employees Exposed 272

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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