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Registry of Toxic Effects of Chemical Substances (RTECS)

Acrylic acid, 2-hydroxypropyl ester

RTECS #

AT1925000

CAS #

999-61-1

Updated

September 2013

Molecular Weight

130.16

Molecular Formula

C6H10O3

Synonyms

1,2-Propanediol, 1-acrylate
2-Hydroxypropyl acrylate
2-Hydroxypropyl acrylate (ACGIH)
2-Propenoic acid, 2-hydroxypropyl ester (9CI)
beta-Hydroxypropyl acrylate
Propylene glycol monoacrylate

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /human 0.1%/48HCODEDG 57,21,2007

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mouse lethal dose (50 percent kill): 1056 mg/kgTOLED5 11,125,1982
oral/rat lethal dose (50 percent kill): 250 mg/kg85INA8 5,320,1986
skin/rabbit lethal dose (50 percent kill): 160 µL/kgAIHAAP 30,470,1969

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 ppm (skin, sen)DTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 ppm (2.8 mg/m3), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 ppm (2.8 mg/m3), Skin, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 ppm (3 mg/m3), skin, MAY2011
Occupational Exposure Limit-FRANCEVME 0.5 ppm (3 mg/m3), Skin, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 ppm (3 mg/m3), skin, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.5 ppm (3 mg/m3), skin, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 ppm (3 mg/m3) (skin), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 ppm (2.8 mg/m3), skin, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.5 ppm (2.9 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0.5 ppm (2.7 mg/m3), JUL2005
Occupational Exposure Limit-RUSSIAtime-weighted average 1 mg/m3, short term exposure limit 3 mg/m3, Skin, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 0.5 ppm (2.7 mg/m3), skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 3 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 ppm (2.7 mg/m3), skin, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 2-HYDROXYPROPYL ACRYLATE-air10H time-weighted average 0.5 ppm (Sk)NIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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