06/08/2018: Lab Advisory: CDC Recommendations for Managing and Reporting Shigella Infections with Possible Reduced Susceptibility to Ciprofloxacin

CDC's Laboratory Outreach Communication System (LOCS)

Audience: Clinical and public health laboratories

Subject: Update to CDC Recommendations for Managing and Reporting Shigella Infections with Possible Reduced Susceptibility to Ciprofloxacin

Level: Laboratory Advisory – Provides important information for a specific incident or situation; contains recommendations or actionable items to be performed by public health officials, laboratorians, and/or clinicians; may not require immediate action

Dear LOCS members,

Drug-resistant, Shigella sp. bacteria

The CDC Health Alert Network recently published an update to the current recommendations on management and reporting of Shigella infections that have been treated with ciprofloxacin or azithromycin, and resulted in possible clinical treatment failure. (See the original HAN, published on April 18, 2017.)

Clinicians are the principal intended target for this update, but we would like all clinical and public health laboratories to be aware of these recommendations because they may result in laboratories receiving additional samples for testing or requests for technical consultation.

Sincerely,

Laboratory Outreach Communication System