About the Public Health Genomics and Precision Health Knowledge Base

COVID-19 GPH is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other materials that captures emerging discoveries and applications of genomics, molecular and other precision medicine and precision public health tools in the investigation and control of COVID-19. Contents include PubMed records via an automated pubmed search algorithm, preprint records from NIH iCite, the relevant information from many media sources picked by experts, and linkages to contents from our curated PHGKB databases. See the current edition.

This database includes general CDC and NIH public health information on specific diseases and health related topics. When available, the database displays genomic information from various CDC and NIH web pages. Users are also encouraged to conduct searches of CDC and NIH websites for additional information.

This database contains CDC-authored scientific publications on genomics and precision health-related topics, and includes articles on infectious diseases, reproductive health, newborn screening, birth defects, developmental disabilities, genetic testing, chronic diseases such as cancer and diabetes, environmental and occupational health, laboratory methods, bioinformatics, and statistical methods. See the current edition.

This database includes published scientific literature on evidence-based translation of genomic and precision health discoveries into improved health care and population health, featuring information on topics that include reproductive health, birth defects, newborn screening, chronic diseases such as cancer and diabetes, pharmacogenomics, and family health history, guidelines and recommendations. View Data Selection Criteria

Genomics Precision Health (GPH): includes published scientific literature on evidence-based translation of genomic discoveries into improved health care and population health.
Non-Genomics Precision Health (non-GPH): includes published scientific literature on the translation of big data, data science and machine learning methods into improved health care and population health.

This database contains guidelines from the Genomics and Precision Health Database, sorted according to the highest evidence tier level that could be assigned to recommendations from each guideline. The sorting process is based on our previous method for classifying genomic applications (described in Clinical Pharmacology and Therapeutics, 2014), except that guideline documents rather than clinical scenarios are sorted according to evidence level).

The State Public Health Genomics Programs database has information about state public health programs and activities relevant to genomics. States have implemented genomics applications for Hereditary Breast and Ovarian Cancer syndrome, Lynch Syndrome, Familial Hypercholesterolemia, newborn screening, and more. Find relevant information from your own state or learn about what’s been accomplished in other states. You can filter results by condition and resource type (data, programs, education, policy, tools, and general information. You can also view the content of the database using State Genomics Implementation Map.

This database includes published scientific literature, popular press articles, tools, and databases on the emerging role of pathogen genomics and host-pathogen interactions in infectious disease control and prevention. It includes information on methods, evolution and pathogenicity, detection and diagnosis, outbreaks, epidemiology and transmission, antimicrobials, and vaccines and host-pathogen interactions. The database contains items from all previous weekly editions of Advanced Molecular Detection Clips, as well as from the current edition. Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. View Data Selection Criteria. See the current edition.