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The Global Standardized Hypertension Treatment Project

The Problem

Where We Work

  • Barbados
  • Colombia
  • Malawi

Key Partners

  • Pan American Health Organization
  • Health Caribbean Coalition
  • University of West Indies
  • Colombia Ministry of Health
  • Lighthouse Welcome Trust
  • Baobab

Cardiovascular diseases (CVD), such as heart attack and stroke, are responsible for almost one in three deaths worldwide. Raised blood pressure, otherwise known as hypertension, is the main risk factor for CVD and is responsible for over nine million largely preventable deaths globally each year.

The broad-scale control of hypertension is challenging yet feasible for countries across the income spectrum, including in low and middle income countries. Successful treatment of hypertension involves the prescription, availability and adherence to appropriate medications, and sustained long-term monitoring and adjustment of medications. Control is hindered by complex treatment regimens, limited availability and affordability of medications, and health care systems that are overburdened and under-resourced.

The CDC, Pan American Health Organization (PAHO) and other regional and global partners are collaborating to launch the Global Standardized Hypertension Treatment Project. This project involves the development and implementation of a framework for standardizing the treatment of hypertension using medications. The approach was inspired by successful infectious disease models such as those used in global tuberculosis and HIV management. Central elements include structured treatment with a core set of medications, treatment protocols with targets, and patient cohort monitoring. The project design aims to be feasible and flexible so it can be applied worldwide and complement existing hypertension guidelines.


Project implementation is first focusing on the Latin American and Caribbean region. In March 2013, CDC and PAHO convened experts, including physicians, pharmacologists, epidemiologists, and other leadership from ministries of health, professional organizations and institutions in the region to support the development of the framework for improving hypertension control worldwide. Key components include:

  • Medication Treatment: Identification of a core set of medications appropriate for the treatment of most adults with hypertension.
  • Availability of Core Medications: Identification of mechanisms to increase the broad scale availability of the core set of medications.
  • Key Elements of Care Delivery: Recommendations for key elements of care delivery to support effective hypertension treatment were made.

Vision for Growth

The project’s next steps include expanding regional and global partner engagement and implementation. Lessons learned from regional implementation will inform global dissemination of the framework to improve hypertension control worldwide. In addition, the Global Standardized Hypertension Treatment Project will be the source for the structured treatment approach applied in the PEPFAR-supported HIV clinics.


For More Information

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  • This slide set provides a general overview of the Global Standardized Hypertension Treatment Project. You can use it to learn and inform potential clinical and public health partners about the project. GSHTP Slide Set
  • This summary explains the process that was undertaken to develop the Global Standardized Hypertension Treatment Project framework and provides results from a regional workshop designed to refine elements for implementation in the Americas. GSHTP Workshop Summary
  • Following the Latin American and Caribbean regional meeting where experts agreed upon a core set of medications, most of these medications were added to the strategic fund medication list, making them less expensive for countries to buy in the Americas. Learn more about the PAHO Strategic Fund
  • Page last reviewed: October 8, 2014
  • Page last updated: October 8, 2014
  • Content source: Global Health
  • Notice: Linking to a non-federal site does not constitute an endorsement by HHS, CDC or any of its employees of the sponsors or the information and products presented on the site. The U.S. Government's Official Web PortalDepartment of Health and Human Services
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