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Behind the Model

Purpose

  • Web series sharing the behind-the-scenes work of CFA and partners in generating models, forecasts, and other analytic products.
  • Aim to provide a high-level overview of methods and practical applications of our work.
  • Written for public health practitioners, healthcare providers, and the public.
Dark blue background with orange waves in two corners. White text on top that says "Center for Forecasting and Outbreak Analytics" and "Behind the Model"

Wastewater-Informed Forecasting

CFA is building public health modeling tools that use signal fusion, in which data streams from multiple sources are used to produce more accurate modeling and analytics. In one example of this work, we are partnering with the National Wastewater Surveillance System (NWSS) and the National Center for Immunization and Respiratory Diseases (NCIRD) to use wastewater data alongside hospital admissions data to forecast COVID-19 hospital admissions at the state and national levels. These additional data could improve forecasts at critical times, such as when entering a surge in transmission.

Image of water flowing out of pipe
Monitoring pathogens in wastewater can help track community spread of COVID-19 and other diseases.

Estimating Impact of Updated Isolation Guidance

We estimated the potential impact of CDC’s updated respiratory virus isolation guidance on an individual’s COVID-19 transmission potential. Our analysis found little difference on average for the likelihood that someone with COVID-19 would spread it to others under the updated isolation guidance compared with the previous guidance.

Blue mask outlined in black next to a coronavirus image with darker blue crowns.
Post-isolation precautions are a key feature of the updated guidance.

Improving CDC’s Tools for Assessing Epidemic Growth

CFA is building modeling tools and computational pipelines so that we can analyze data quickly and accurately in response to outbreaks. Our goal is to make these tools accessible to federal, state, tribal, territorial, local, and academic partners. One of these efforts is to estimate the time-varying reproductive number, Rt, a measure that helps us quickly assess whether infections are increasing or decreasing.

Idealized Rt chart. Transmission chain of 3 infected generation persons to 4 infected generation persons.
Rt is a data-driven quantity. We identify all the individuals infected on a particular date (this is referred to as the "infectee generation", with four newly infected persons), and divide by the number of people who caused those infections (or the "parents" of those cases, making up the "infector generation").