Guide to the Application of Genotyping to Tuberculosis Prevention and Control

Appendix B: References and Useful Resources

NTGSN Special Issue References

In response to the increase in the number of reported tuberculosis cases in the United States, CDC funded regional laboratories to provide genotyping services to support TB prevention and control programs in outbreak investigations and to conduct studies on using genotyping in TB epidemiology and control. This network was expanded to include sentinel surveillance sampling in 1996 when CDC established the National Tuberculosis Genotyping and Surveillance Network (NTGSN) as a 5-year project. NTGSN comprised CDC and seven laboratories and seven sentinel surveillance sites in the United States. Sentinel surveillance sites included the states of Arkansas, Maryland, Massachusetts, Michigan, and New Jersey and six counties in California (Alameda, Contra Costa, Marin, San Mateo, Santa Clara, and Solano); and four counties in Texas (Dallas, Tarrant, Cameron, and Hidalgo). The November 2002 special issue of Emerging Infectious Diseases contains the following reports of the studies resulting from the NTGSN. The special issue of the journal is available at

Navin TR, McNabb SJN, Crawford, JT. The continued threat of tuberculosis. Emerg Infect Dis 2002;8:1187.

Castro KG, Jaffe HW. Rationale and methods for the National Tuberculosis Genotyping and Surveillance Network. Emerg Infect Dis 2002;8:1188-91.

Crawford JT, Braden R, Schable BA, Onorato IM. National Tuberculosis Genotyping and Surveillance Network: design and methods. Emerg Infect Dis 2002;8:1192-5.

Ellis BA, Crawford JT, Braden CR, et al. Molecular epidemiology of tuberculosis in a sentinel surveillance population. Emerg Infect Dis 2002;8:1197-209.

Braden CR, Crawford JT, Schable BA. Quality assessment of Mycobacterium tuberculosis genotyping in a large laboratory network. Emerg Infect Dis 2002;8:1210-5.

Sun SJ, Bennett DE, Flood J, Loeffler AM, Kammerer S, Ellis BA. Identifying the sources of tuberculosis in young children: a multistate investigation. Emerg Infect Dis 2002;8:1216-23.

Bennett DE, Onorato IM, Ellis BA, et al. DNA fingerprinting of Mycobacterium tuberuclosis isolates fromepidemiologically linked case pairs. Emerg Infect Dis 2002;8:1224-9.

Munsiff SS, Bassoff T, Nivin B, et al. Molecular epidemiology of multidrug-resistant tuberculosis, New York City, 1995-1997. Emerg Infect Dis 2002;8:1230-8.

Sharnprapai S, Miller AC, Suruki R, et al. Genotyping analyses of tuberculosis cases in U.S.- and foreign-born Massachusetts residents. Emerg Infect Dis 2002;8:1239-45.

Dillaha JA, Zhenhua Y, Ijaz K, et al. Transmission of Mycobacterium tuberculosis in a rural community, Arkansas, 1945-2000. Emerg Infect Dis 2002;8:1246-8.

Latha M, Mukasa LN, Hooepr N, et al. Cross-jurisdictional transmission of Mycobacterium tuberculosis in Maryland and Washington, D.C., 1996-2000 linked to the homeless. Emerg Infect Dis 2002;8:1249-51.

McElroy PD, Sterling TR, Driver CR, et al. Use of DNA fingerprinting to investigate a multiyear, multistate tuberculosis outbreak. Emerg Infect Dis 2002;8:1251-8.

Ijaz K, Yang Z, Matthews S, Bates JH, Cave MD. Mycobacterium tuberculosis transmission between cluster members with similar fingerprint patterns. Emerg Infect Dis 2002;8:1257-9.

Northrus JM, Miller AC, Nardell E, et al. Estimated costs of false laboratory diagnoses of tuberculosis in three patients. Emerg Infect Dis 2002;8:1264-70.

Cronin, WA, Golub JE, Lathan MJ, et al. Molecular epidemiology of tuberculosis in a low- to moderate-incidence state: are contact investigations enough? Emerg Infect Dis 2002;8:1271-9.

Kong P, Tapy J, Calixto P, et al. Skin-test screening and tuberculosis transmission among the homeless. Emerg Infect Dis 2002;8:1280-4.

Miller AC, Sharnprapai S, Suruki R, Corkren E, Nardell EA, Driscoll JR. Impact of genotyping of Mycobacterium tuberculosis on public health practice in Massachusetts. Emerg Infect Dis 2002;8:1285-9.

Oh P, Granich R, Scott J, et al. Human exposure following Mycobacterium tuberculosis infection of multiple animal species in a metropolitan zoo. Emerg Infect Dis 2002;8:1290-3.

Cowan LS, Crawford JT. Genotype analysis of Mycobacterium tuberculosis isolates from a sentinel surveillance population. Emerg Infect Dis 2002;8:1294-1302.

Lok KH, Benjamin WH, Kimerling ME, et al. Molecular typing of Mycobacterium tuberculosis strains with a common two-band IS6110 pattern. Emerg Infect Dis 2002;8:1303-5.

Driscoll JR, Bifani PJ, Mathema B, et al. Spoligologos: a bioinformatic approach to displaying and analyzing Mycobacterium tuberculosis data. Emerg Infect Dis 2002;8:1306-9.

Lok KH, Benjamin WH, Kimerling ME, et al. Molecular differentiation of Mycobacterium tuberculosis strains without IS6110 insertions. Emerg Infect Dis 2002;8:1310-3.

McNabb SJN, Braden CR, Navin TR. DNA fingerprinting of Mycobacterium tuberculosis: Lessons learned and implications for the future. Emerg Infect Dis 2002;8:1314-9.

Drobniewski F, Balabanova Y, Ruddy M, et al. Rifampin- and multidrug-resistant tuberculosis in Russian civilians and prison inmates: Dominance of the Beijing strain family. Emerg Infect Dis 2002;8:1320-6.

Garcia-Garcia ML, Ponce-de-Leon A, Garcia-Sancho MC, Ferreyra-Reyes L, Palacios-Martinez M, Fuentes J. Tuberculosis-related deaths within a well-functioning DOTS control program. Emerg Infect Dis 2002;8:1327-33.

Drake WP, Pei Z, Pride DT, Collins RD, Cover TL, Blaser MJ. Molecular analysis of sarcoidosis tissues for Mycobacterium species DNA. Emerg Infect Dis 2002;8:1334-41.

Hughes AL, Friedman R, Murray M. Genomewide pattern of synonymous nucleotide substitution in two complete genomes of Mycobacterium tuberculosis. Emerg Infect Dis 2002;8:1342-6.

Filliol I, Driscoll JR, Soolingen D, et al. Global distribution of Mycobacterium tuberculosis spoligotypes. Emerg Infect Dis 2002;8:1347-9.

Miltgen, J, Morillon M, Koeck JL, et al. Two cases of pulmonary tuberculosis caused by Mycobacterium tuberculosis subsp. Canetti. Emerg Infect Dis 2002;8:1350-2.

Morens DM. At the deathbed of consumptive art. Emerg Infect Dis 2002;8:1353-8.K