Guide to the Application of Genotyping to Tuberculosis Prevention and Control

Developing a Tuberculosis Genotyping Program

Initiating a TB genotyping program requires planning and coordination. In this chapter, we discuss the key components of the planning and coordination process that TB programs should consider in developing a genotyping plan. For each component, we provide suggestions about how a TB program may proceed. In Chapter 6, Applying Genotyping Results to Tuberculosis Control Practices, we will discuss how the specific procedures described here can be utilized to interpret and take action on new genotyping results as they are reported by the genotyping laboratories.

In the initial phase of establishing a TB genotyping program, it is important to develop an effective system for communication among the various persons who will be involved. It is also important to provide clear explanations of the goals of the program. The CDC Tuberculosis Genotyping Program is not a research program, but rather a public health service to enhance TB control. Over time, genotyping M. tuberculosis isolates will help identify TB cases that are the result of recent transmission.